A nurse is reinforcing teaching for a female client who has multiple sclerosis and a new prescription for dantrolene.
Which of the following client statements indicates an understanding of the teaching?.

"I should take this medication when my spasms are bad.”.

"I need to notify my provider if I don't get some relief from my muscle spasms within 3 months.”.

"I am glad this medication is safe to take if I get pregnant.”.

"I should return to the clinic to have my calcium level checked every 6 weeks.”.

Answer and Explanation

The Correct Answer is B

The correct answer is Choice B

Choice A rationale: Dantrolene is a direct-acting skeletal muscle relaxant that works by inhibiting calcium release from the sarcoplasmic reticulum in muscle cells, thereby reducing muscle contraction. It is not intended for as-needed use during acute spasms but requires consistent dosing to maintain therapeutic levels. Intermittent use undermines its pharmacokinetics and may lead to subtherapeutic effects. The half-life of dantrolene is approximately 8.7 hours, and steady-state levels are necessary for optimal spasticity control in multiple sclerosis.

Choice B rationale: Dantrolene’s therapeutic effect on muscle spasticity may take several weeks to manifest due to its mechanism of action involving gradual reduction in intracellular calcium availability. If no improvement is noted within 3 months, it may indicate inadequate response or the need for dosage adjustment. Monitoring for efficacy is essential, as prolonged use without benefit increases risk of hepatotoxicity. Liver function tests should be monitored regularly. Normal ALT levels are 7–56 units/L; elevations may signal toxicity.

Choice C rationale: Dantrolene is classified as pregnancy category C, indicating that risk to the fetus cannot be ruled out. Animal studies have shown adverse effects, and there are no adequate human studies confirming safety during pregnancy. Therefore, it is not considered safe without careful risk-benefit analysis. Teratogenicity and fetal toxicity are concerns due to its action on muscle fibers and potential systemic effects. Pregnant clients should consult their provider before initiating or continuing dantrolene therapy.

Choice D rationale: Dantrolene does not directly affect calcium levels in the bloodstream. Its mechanism involves inhibition of calcium release within muscle cells, not systemic calcium metabolism. Routine calcium monitoring is not required unless the client has a separate condition affecting calcium homeostasis. Normal serum calcium levels range from 8.5 to 10.5 mg/dL. The primary lab concern with dantrolene is hepatotoxicity, necessitating regular liver function tests, not calcium surveillance. This statement reflects a misunderstanding of the drug’s effects.

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Correct Answer is ["10"]

Explanation

Step 1 is to calculate the amount of hydroxyzine HCL in each mL of the oral suspension. This is done by dividing the total amount of hydroxyzine HCL (25 mg) by the total volume (5 mL), which gives us 5 mg/mL. Step 2 is to calculate the volume of oral suspension that contains 50 mg of hydroxyzine HCL. This is done by dividing the prescribed dose (50 mg) by the concentration of the oral suspension (5 mg/mL). So, 50 mg ÷ 5 mg/mL = 10 mL.

So, the correct answer is 10 mL.

A. Switch phenytoin brands with each refill. B. Alter the phenytoin administration regimen each week. C. Phenytoin turns urine blue. D. Alcohol increases the chance of phenytoin toxicity.

Correct Answer is D

Explanation

Choice A rationale:

Switching brands of phenytoin can lead to variations in drug absorption and serum drug levels, potentially leading to a loss of seizure control or toxicity. Therefore, this is not a correct instruction.

Choice B rationale:

Altering the phenytoin administration regimen each week can lead to fluctuations in serum drug levels, potentially leading to a loss of seizure control or toxicity. Therefore, this is not a correct instruction.

Choice C rationale:

Phenytoin does not turn urine blue. This is a side effect associated with some other medications, but not phenytoin. Therefore, this is not a correct instruction.

Choice D rationale:

Alcohol can increase serum phenytoin levels, potentially leading to toxicity. Therefore, this is a correct instruction.

So, the correct answer is D. Alcohol increases the chance of phenytoin toxicity.

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A nurse is reinforcing teaching for a female client who has multiple sclerosis and a new prescription for dantrolene. Which of the following client statements indicates an understanding of the teaching?.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

nurse is preparing to administer hydroxyzine HCL 50 mg PO. Available is hydroxyzine oral suspension 25 mg/5 mL. How many mL should the nurse administer? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero

Correct Answer is ["10"]

Explanation

A nurse is reinforcing discharge teaching with a client who has a prescription for phenytoin.Which of the following instructions should the nurse include in the teaching?.

Correct Answer is D

Explanation

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A nurse is reinforcing teaching for a female client who has multiple sclerosis and a new prescription for dantrolene.
Which of the following client statements indicates an understanding of the teaching?.