A nurse is reviewing the ECG tracing strip of a client who is receiving telemetry monitoring.
The nurse should locate the S-T segment at which of the following locations on the electrocardiographic waveform.

Choice A rationale

Postterm pregnancy, defined as a gestation extending beyond 42 weeks, is not a contraindication for misoprostol. In fact, it is a common indication for labor induction, as the placenta may begin to deteriorate, increasing the risk of fetal distress and meconium aspiration. Misoprostol, a prostaglandin E1 analog, helps ripen the cervix and stimulate uterine contractions. This pharmacologic action is beneficial in initiating labor in postterm pregnancies.

Choice B rationale

Transverse fetal lie is an obstetrical position where the fetus is lying sideways across the uterus. This position poses a significant risk of complications during vaginal birth, including uterine rupture and umbilical cord prolapse. Therefore, any attempt to induce labor with a medication like misoprostol is contraindicated. Cesarean delivery is typically the preferred method of delivery in cases of persistent transverse lie to ensure a safe delivery for both mother and fetus.

Choice C rationale

Intrauterine growth restriction (IUGR) is a condition where a fetus is smaller than expected for gestational age. It is not a contraindication for misoprostol. Often, IUGR is an indication for labor induction to prevent further fetal compromise. Misoprostol is a commonly used medication for this purpose, as it helps to initiate cervical ripening and uterine contractions, which can lead to a successful vaginal delivery.

Choice D rationale

A history of a cesarean section is a significant contraindication for misoprostol because it substantially increases the risk of uterine rupture. Misoprostol causes potent uterine contractions that can place undue stress on the uterine scar from the previous surgery. The risk of rupture is a life-threatening complication for both the mother and the fetus. Therefore, other methods of labor induction or a planned repeat cesarean section are often considered. *.

Choice A rationale

Metformin extended-release tablets are designed with a special matrix that releases the medication gradually over time. Crushing or chewing the tablet would destroy this matrix, leading to an immediate and potentially unsafe release of the entire dose. This could cause a sudden drop in blood glucose and increase the risk of adverse gastrointestinal side effects.

Choice B rationale

Metformin is typically recommended to be taken with the evening meal to minimize gastrointestinal side effects such as nausea and diarrhea, which are common when starting the medication. Taking it in the morning on an empty stomach could increase the severity of these adverse effects due to the rapid concentration increase in the gastrointestinal tract.

Choice C rationale

Metformin is not associated with weight gain; in fact, it is often associated with a small amount of weight loss. This is due to its effect on reducing appetite and its ability to improve insulin sensitivity, which can help regulate metabolism and prevent the weight gain often seen with other diabetes medications.

Choice D rationale

Metformin is best taken with a meal to enhance its absorption and to mitigate common gastrointestinal side effects. Taking it on an empty stomach can increase the likelihood and severity of adverse effects like nausea, vomiting, and diarrhea because the medication can directly irritate the gastrointestinal mucosa