A nurse is reviewing the list of current medications for a client who is to start a new prescription for carbamazepine. The nurse should identify which of the following medications interacts with carbamazepine.

Estrogen-progestin combination

Nicotine transdermal system

Diphenhydramine

Beclomethasone

Answer and Explanation

The Correct Answer is A

A. Estrogen-progestin combination:
Correct Answer: This medication interacts with carbamazepine.
Explanation: Carbamazepine is known to induce certain liver enzymes, including cytochrome P450 enzymes. These enzymes play a role in the metabolism of various medications, including estrogen-containing oral contraceptives (estrogen-progestin combinations). Carbamazepine can increase the metabolism of estrogen-progestin combinations, potentially reducing their effectiveness and increasing the risk of contraceptive failure. Therefore, this interaction can lead to decreased contraceptive efficacy and the potential for unintended pregnancy.
B. Nicotine transdermal system:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Nicotine replacement therapies, such as nicotine transdermal systems, are not known to have significant interactions with carbamazepine. These therapies are primarily used to aid in smoking cessation and do not share metabolic pathways with carbamazepine.
C. Diphenhydramine:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Diphenhydramine is an antihistamine used for allergies and as a sleep aid. It does not have a well-established interaction with carbamazepine. However, it's important to note that carbamazepine can have central nervous system (CNS) effects, so caution should be exercised when combining it with other medications that also have CNS effects.
D. Beclomethasone:
Incorrect Explanation: This medication does not interact with carbamazepine.
Explanation: Beclomethasone is a corticosteroid used to manage inflammation associated with conditions like asthma and allergic rhinitis. It is not known to interact with carbamazepine. These two medications have different mechanisms of action and do not share significant metabolic pathways.

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Correct Answer is D

Explanation

The correct sequence of steps for mixing regular insulin and NPH insulin in the same syringe is as follows:

D. Inject air into the NPH insulin vial.

B. Inject air into the regular insulin vial.

C. Withdraw the regular insulin from the vial.

A. Withdraw the NPH insulin from the vial.

So, the nurse should first inject air into the NPH insulin vial.

A. "I should stay upright for at least 15 minutes after taking this medication." B. "I should take this medication with 8 ounces of milk." C. "I should take an antacid with this medication to prevent stomach upset." D. "I should notify my provider if my stools turn black.

Correct Answer is D

Explanation

A. "I should stay upright for at least 15 minutes after taking this medication.": This advice is usually given with medications like bisphosphonates to prevent esophageal irritation. It is not necessary for ferrous gluconate.
B. "I should take this medication with 8 ounces of milk.": Iron supplements should not be taken with milk or other dairy products because they can interfere with iron absorption.
C. "I should take an antacid with this medication to prevent stomach upset.": Antacids can also interfere with iron absorption and should be taken separately from iron supplements.
D. "I should notify my provider if my stools turn black."
Ferrous gluconate is an iron supplement used to treat iron deficiency anemia. One common side effect of iron supplementation is the darkening of stools, often to a black color. This is not harmful but is important for the client to be aware of. It is due to the reaction of iron with the acids and enzymes in the gastrointestinal tract.

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A nurse is reviewing the list of current medications for a client who is to start a new prescription for carbamazepine. The nurse should identify which of the following medications interacts with carbamazepine.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse mixing regular insulin and NPH insulin in the same syringe prior to administering it to a client who has diabetes mellitus. Which of the following actions should the nurse take first?

Correct Answer is D

Explanation

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Correct Answer is D

Explanation

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