A nurse is reviewing the medication administration record for a client who has cancer and is receiving morphine via a PCA pump. Which of the following prescriptions should the nurse clarify with the provider?
Nalbuphine
Acetaminophen
Ondansetron
Insulin glargine
The Correct Answer is A
Nalbuphine is also an opioid like morphine. Opioids suppress the central respiratory centers leading to respiratory depression. Use of two opioids increases their levels in blood raising the risk of respiratory depression even higher which is fatal.
The other drugs do not have any significant interaction with morphine. C- An analgesic , C- Ondansetron- antiemetic, Insulin glargine- an form of insulin used in diabetes
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Both sildenafil and nitroglycerin are vasodilators and can lead to severe hypotension when used together. Sildenafil acts by inhibiting phosphodiesterase 5 (PDE 5), an enzyme that breaks down cGMP, which regulates blood flow in the penis. The medication also results in the dilation of blood vessels in the lungs, which is beneficial for treating pulmonary arterial hypertension.
B, C, D- No interactions with nitroglycerin
Correct Answer is B
Explanation
Propofol causes positive modulation of the inhibitory function of the neurotransmitter gamma-aminobutyric acid (GABA) through GABA-A receptors. It also enhances GABA's effects leads to increased chloride influx into neurons, causing hyperpolarization and decreased neuronal activity. This results in the sedative and hypnotic effects for which propofol is used during anesthesia. Propofol can cause respiratory depression when levels in the blood are high and hence respiratory rate should be monitored closely
A-Propofol is likely to cause bradycardia due to depression of central cardiac centers
C-Propofol has no effect on bowel function
D-Propofol can cause hypothermia when used in anesthesia but not as critical as respiratory depression
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