A nurse is teaching a newly licensed nurse about administering naloxone to treat a client who is experiencing opioid toxicity. Which of the following information should the nurse include in the teaching?

D. Statin medications like lovastatin can rarely cause liver enzyme abnormalities, so baseline liver function tests are typically recommended before starting therapy to establish a baseline. This statement is correct and important to include in the teaching. Regular monitoring of liver function tests may also be recommended during treatment to detect any potential liver-related side effects early.

A. Lovastatin is a statin medication used to lower cholesterol levels. Dairy products do not interact directly with lovastatin, so there is no specific need to avoid dairy while taking this medication.

B Lovastatin extended release formulations are designed to release the medication slowly over time. Crushing or chewing extended release tablets can disrupt this mechanism and lead to unintended rapid absorption of the medication.

C. Statin medications, including lovastatin, can be taken at any time of day. There is no specific requirement to take lovastatin in the morning.

C. Dehydration often leads to dryness of oral mucous membranes due to decreased saliva production. Improved hydration status should lead to moist oral mucous membranes as the client's fluid balance is restored. This is a positive sign that fluid replacement therapy is effective and the client's hydration status is improving.

A. In a dehydrated client, low fluid volume can lead to hypotension (low blood pressure). Effective IV fluid replacement should improve circulating blood volume and subsequently normalize blood pressure. Decreased blood pressure would indicate that the client's condition is improving with adequate fluid replacement. However, this is not always a definitive indicator on its own as other factors can influence blood pressure.

B. An increased heart rate may initially be observed in a dehydrated client. However, as fluid replacement corrects the volume deficit, the heart rate should normalize or decrease to baseline levels. Therefore, a decrease in heart rate would actually indicate effective treatment.

D. Thirst is a symptom of dehydration where the body signals a need for fluids. Effective IV fluid replacement should address the underlying cause of thirst by restoring fluid balance. Therefore, a decrease in excessive thirst would indicate that the client's hydration needs are being met adequately.