A patient taking a calcium channel blocker is seen in the clinic and diagnosed with drug toxicity. When collecting the nursing history, what finding would indicate the likely cause of this drug toxicity?
The ingestion of grapefruit juice
Intake of alcohol
Intake of aged cheese
The use of eggs in the diet
The Correct Answer is A
A. The ingestion of grapefruit juice: Grapefruit juice inhibits CYP3A4 and can raise plasma levels of many calcium channel blockers, causing toxicity.
B. Intake of alcohol: Alcohol can interact with drugs but is not the classic cause of CCB toxicity listed here.
C. Intake of aged cheese: Aged cheese interacts with MAO inhibitors (tyramine reaction), not calcium channel blockers.
D. The use of eggs in the diet: Eggs do not cause calcium channel blocker toxicity.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Hypoglycemia: Hypokalemia is not primarily associated with hypoglycemia.
B. Hyperreflexia: Hypokalemia typically causes muscle weakness and decreased reflexes (not hyperreflexia).
C. Cardiac dysrhythmias: Hypokalemia (K⁺ 3.0) predisposes to cardiac conduction disturbances and dysrhythmias-monitor ECG and replace potassium as ordered.
D. Increased appetite: Increased appetite is not an expected physiologic response to hypokalemia from loop diuretics.
Correct Answer is B
Explanation
A. Weight gain: Weight gain is more consistent with undertreatment (hypothyroidism), not over-replacement.
B. Tachypnea: Excess levothyroxine produces hyperthyroid signs (increased metabolic rate) -tachycardia and often increased respiratory rate (tachypnea), heat intolerance, nervousness, and weight loss.
C. Decreased temperature: Overdose would cause increased body temperature / heat intolerance, not decreased temperature.
D. Bradycardia: Bradycardia is a sign of underreplacement (hypothyroidism); overreplacement causes tachycardia.
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