According to Boyle's law, as the volume of a container decreases.

A. autoimmune disease: when the immune system targets the body’s own tissues (e.g., Hashimoto thyroiditis), it is classified as an autoimmune disease.
B. tissue rejection reaction: tissue rejection refers to immune attack against a transplanted (non-self) organ, not the person’s own tissue.
C. secondary immune response: a secondary immune response refers to the heightened response on re-exposure to an antigen (memory response), not self-destruction of an organ.
D. type IV hypersensitivity: some autoimmune diseases involve cell-mediated (type IV) mechanisms, but autoimmune disease is the broader correct classification; not all autoimmune thyroid destruction is exclusively type IV.

A. Submucosa: submucosa is connective tissue containing blood/lymph vessels and glands, not the epithelial lining.
B. Muscularis: muscularis is smooth muscle (inner circular/outer longitudinal layers) responsible for peristalsis, not epithelial.
C. Mucosa: the mucosa includes the epithelial lining, lamina propria, and may contain folds and mucus-secreting glands (e.g., gastric mucosa).
D. Serosa: serosa is the outermost connective tissue/mesothelial covering of the gut, not the epithelial absorptive/secreting layer.