An unconscious patient who was transferred from surgery to the postanesthesia care unit (PACU) 15 minutes ago has an oxygen saturation of 89%. Which action should the nurse take first?

A. Smoking has been associated with an increased risk of developing osteoarthritis, particularly in the knees and hips. Smoking may contribute to inflammation and oxidative stress, which can exacerbate joint damage.

D. Aging is a significant risk factor for osteoarthritis. As individuals age, the cartilage in their joints may naturally deteriorate over time, leading to the development of osteoarthritis.

E. Obesity is a well-established risk factor for osteoarthritis, particularly in weight-bearing joints such as the knees and hips. Excess body weight places increased stress on the joints, leading to accelerated wear and tear of the joint cartilage.

B. Bacteria are not typically associated with the development of osteoarthritis. Osteoarthritis is primarily a non-inflammatory condition related to wear and tear on the joints rather than an infectious process.

C. Diuretics are medications used to treat conditions such as hypertension and edema by increasing urine output. There is no direct evidence linking diuretic use to the development of osteoarthritis.

D. Excessive thyroid hormone replacement therapy, leading to hyperthyroidism, can accelerate bone turnover and increase the risk of osteoporosis. Hyperthyroidism can disrupt normal bone remodeling processes, leading to decreased bone mineral density and increased fracture risk.

A. NSAIDs are commonly used to reduce inflammation and relieve pain. While short-term or occasional use of NSAIDs is generally safe, long-term use or high doses of NSAIDs may be associated with an increased risk of osteoporosis and bone fractures.

B. Anticoagulants, such as warfarin and heparin, are medications used to prevent blood clot formation. While anticoagulants themselves are not directly associated with osteoporosis risk, prolonged immobilization due to conditions requiring anticoagulation therapy (such as deep vein thrombosis or pulmonary embolism) can increase the risk of osteoporosis and bone loss due to decreased weight- bearing activity.

C. Cardiac glycosides, such as digoxin, are medications used to treat heart failure and certain cardiac arrhythmias. There is no direct evidence to suggest that cardiac glycosides themselves are a risk factor for osteoporosis.