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Ceftazidime 750 mg IV every 12 hours is prescribed for a client with an infection. The directions on the label of the 750 mg vial instruct the nurse to reconstitute with 100 mL sterile water. The reconstituted medication provides how many mg/mL? (Enter numeric value only. If rounding is required, round to the nearest tenth.)
Answer and Explanation

The Correct Answer is ["7.5"]

Here's how to calculate the concentration (mg/mL) of the reconstituted ceftazidime medication

Medication: 750 mg ceftazidime

Diluent: 100 mL sterile water (for reconstitution)

We need to find the concentration (mg/mL) after reconstituting the medication with diluent.

 

Calculation:

Concentration (mg/mL) = Total medication (mg) / Volume of diluent (mL)

Concentration (mg/mL) = 750 mg / 100 mL

Concentration (mg/mL) = 7.5 mg/mL (round to nearest tenth)

Therefore, the reconstituted medication will have a concentration of 7.5 mg/mL.


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Related Questions

Correct Answer is ["0.5"]

Explanation

Here's how to calculate the volume (mL) of filgrastim the nurse should administer:

1. Client weight conversion:

Client weight: 132 pounds

Medication dosage is based on weight per kilogram (kg).

Conversion factor: 1 kg = 2.205 lbs

Client weight (kg): 132 pounds / 2.205 lbs/kg = 60 kg (round to nearest whole number)

2. Filgrastim dosage:

Prescribed dose: 5 mcg/kg/day (given)

3. Daily filgrastim amount:

Daily dose (mcg) = Dose (mcg/kg/day) x Client weight (kg)

Daily dose (mcg) = 5 mcg/kg/day * 60 kg

Daily dose (mcg) = 300 mcg (round to nearest whole number)

4. Filgrastim vial concentration:

The medication is available in 480 mcg/0.8 mL. This indicates the concentration of filgrastim in the vial is 480 mcg per 0.8 mL.

5. We need to find the volume (mL) to administer that provides the daily dose (300 mcg) based on the medication concentration (480 mcg/0.8 mL).

Volume to administer (mL) = Daily dose (mcg) / Concentration (mcg/mL)

Volume to administer (mL) = 300 mcg / (480 mcg/0.8 mL)

To perform the division accurately, we need the concentration in the same units (mcg/mL) for both the numerator and denominator.

We can achieve this by multiplying the vial concentration (480 mcg/0.8 mL) by a factor that converts the denominator (0.8 mL) to 1 mL.

Factor = 1 mL / 0.8 mL = 1.25 (since 1.25 x 0.8 mL = 1 mL)

Apply the factor to adjust the concentration in the denominator:

Adjusted concentration = 480 mcg/0.8 mL * 1.25 = 600 mcg/mL

Now, calculate the volume to administer:

Volume to administer (mL) = 300 mcg / (600 mcg/mL)

Volume to administer (mL) = 0.5 mL (round to nearest tenth as requested)

Therefore, the nurse should administer approximately 0.5 mL of filgrastim subcutaneously.

Correct Answer is ["0.64"]

Explanation

Here's the calculation:

Prescribed dose: 40 mg methylprednisolone

Medication vial concentration: 125 mg per 2 mL (given on the vial label)

We need to find the volume (mL) containing the prescribed dose (40 mg) of methylprednisolone.

Calculation:

Concentration adjustment: The concentration is given in mg per 2 mL. To calculate the medication needed for the 40 mg dose, we need the concentration in mg/mL.

Concentration (mg/mL) = Total mg / Volume (mL)

Concentration (mg/mL) = 125 mg / 2 mL

Concentration (mg/mL) = 62.5 mg/mL

Volume to administer:

Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)

Volume to administer (mL) = 40 mg / 62.5 mg/mL

Volume to administer (mL) = 0.64 mL (round to nearest hundredth)

Therefore, the nurse should administer 0.64 mL of methylprednisolone.

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