Children less than 5 years of age may not fully absorb time released oral medications due to:
Constipation.
Immature kidney function.
Increased gastrointestinal motility.
Decreased gastric acidity.
The Correct Answer is C
Oral drug absorption in young children is determined by developmental differences in gastrointestinal motility, gastric emptying, intestinal enzyme activity, and mucosal surface maturation. In children under 5 years, accelerated and irregular intestinal transit can significantly disrupt the designed pharmacokinetics of extended-release formulations, reducing consistent drug absorption and therapeutic effect.
Rationale:
A. Constipation increases intestinal transit time, which may prolong drug contact with absorptive surfaces and potentially enhance absorption. It does not interfere with the controlled-release mechanism of time-released formulations in children under 5 years.
B. Renal immaturity affects drug excretion and clearance rather than gastrointestinal absorption. Time-release oral medications depend on gastrointestinal transit dynamics, not renal function, making this option unrelated to the absorption issue.
C. Children under 5 have rapid peristalsis and shortened intestinal transit time, reducing controlled drug release and absorption window. This disrupts extended-release formulation kinetics, leading to incomplete or inconsistent systemic drug levels.
D. Reduced gastric acid affects dissolution of acid-dependent drugs but does not significantly impair extended-release medication absorption. Time-release systems are primarily designed for intestinal release, so this factor has minimal impact on overall absorption in this age group.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Transitional objects are psychological attachments that provide emotional security, separation comfort, object permanence, and self-soothing behaviors in toddlers during stress or hospitalization. They reduce anxiety by maintaining continuity between home environment and unfamiliar settings.
Rationale:
A. Providing toys from the playroom does not represent a transitional object. Playroom items are therapeutic distractions but lack personal attachment significance. Toddlers use familiar objects from home for emotional continuity. This option reflects recreational therapy rather than attachment-based coping mechanisms during hospitalization.
B. Purchasing a new stuffed animal does not constitute a true transitional object. These objects must be pre-existing attachments linked to the child's home environment. New items lack established emotional bonding. Therefore, they do not provide effective security reinforcement during hospitalization stress responses.
C. A stuffed animal can function as a transitional object only if previously attached at home. However, the statement is generic and lacks evidence of prior emotional bonding. Without established familiarity, it may not provide true attachment security. Thus, it is incomplete as a correct indicator.
D. A dirty old blanket from home is a classic transitional object used for comfort. It carries familiar scent, texture, and emotional association with caregivers. This promotes attachment stability and reduces separation anxiety. It demonstrates correct understanding of toddler psychological coping during hospitalization.
Correct Answer is B
Explanation
Intramuscular medication administration in toddlers requires consideration of muscle mass, vascular absorption, tissue tolerance, and risk of neuromuscular injury. The developing musculature of children under 2 years limits injectable volume capacity, making dose distribution and appropriate site selection essential for safe pharmacologic delivery.
Rationale:
A. A 3 mL intramuscular injection exceeds recommended tissue capacity for an 18-month-old child. Excessive volume increases risk of pain, muscle fiber damage, poor absorption, and local complications such as induration or nerve compression.
B. A maximum volume of 1 mL is recommended because toddler muscles have limited muscle bulk and reduced tissue distensibility. This volume promotes effective medication absorption while minimizing discomfort, tissue trauma, and leakage from the injection site.
C. A 5 mL injection is appropriate only for larger adult muscle groups with substantial muscular development. In toddlers, this volume can cause severe tissue stretching, impaired absorption, and increased risk of localized injury.
D. Although 2 mL may occasionally be tolerated in older children, it generally exceeds safe limits for most 18-month-olds. Smaller pediatric muscles cannot reliably accommodate this injection volume without increasing tissue irritation and procedural pain.
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