Epinephrine is used to treat cardiac arrest and status asthmaticus because of which of the following actions?

Choice A rationale: Stopping aspirin immediately may not be necessary and can increase the risk of rebound thrombosis. A gradual discontinuation is often recommended.
Choice B rationale: Stopping aspirin 3 days prior to surgery is a common recommendation to minimize the risk of bleeding during and after the surgical procedure.
Choice C rationale: Reducing the aspirin dosage may not be sufficient, and complete discontinuation is often advised before surgery.
Choice D rationale: Continuing aspirin as scheduled can increase the risk of bleeding during and after surgery. It is generally recommended to discontinue aspirin before elective surgical procedures.

Choice A rationale: Allopurinol dosing is not typically adjusted based on target serum drug levels.
Choice B rationale: The absence of gastrointestinal (GI) effects is not a parameter used to adjust the dosing of allopurinol.
Choice C rationale: This is partially correct. Allopurinol dosing is adjusted based on renal function, but specifically, it is adjusted based on serum creatinine levels. The higher the creatinine levels, the lower the dose of allopurinol should be.
Choice D rationale: This is correct. Allopurinol dosing is adjusted based on plasma urate levels. The goal is to reduce uric acid levels in the blood to prevent the formation of urate crystals and subsequent gout attacks. Regular monitoring of plasma urate levels helps determine the effectiveness of the medication, and adjustments can be made to achieve the target urate level.