A patient diagnosed with rheumatoid arthritis is about to begin therapy with Etanercept, a tumor necrosis factor antagonist. The nurse anticipates the patient will be tested for
CYP450 genetic variants.
HLA-B genetic variants.
latent hepatitis B virus.
Blood type and crossmatch.
The Correct Answer is C
Choice A rationale: Testing for CYP450 genetic variants is more relevant for medications metabolized by the cytochrome P450 system.
Choice B rationale: HLA-B genetic variants are more associated with certain drug hypersensitivity reactions, not specifically for etanercept.
Choice C rationale: Etanercept can increase the risk of reactivating latent infections, including hepatitis B. Screening for latent hepatitis B virus is essential before starting therapy.
Choice D rationale: Blood type and crossmatch are not typically required for starting etanercept therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale: Epinephrine is not an antagonist for benzodiazepines. It is primarily used in the treatment of anaphylaxis and cardiac arrest.
Choice B rationale: Atropine is not an antagonist for benzodiazepines. It is used to increase heart rate and treat certain types of poisoning.
Choice C rationale: Flumazenil is a specific antagonist for benzodiazepines. It can be used to reverse the sedative effects of benzodiazepine overdose, such as in the case of the patient taking an excessive amount of lorazepam.
Choice D rationale: Naloxone is an opioid antagonist and would not be effective in reversing the effects of lorazepam overdose.
Correct Answer is B
Explanation
Choice A rationale: Nasal congestion is a common side effect of alpha1-adrenergic blockers, not a cause for concern.
Choice B rationale: Orthostatic hypotension is a potential adverse effect of alpha1- adrenergic blockers like prazosin. It can lead to dizziness and falls, particularly when moving from a lying or sitting position to a standing one.
Choice C rationale: Inhibition of ejaculation is a potential side effect of alpha1- adrenergic blockers but is not of the most concern compared to orthostatic hypotension.
Choice D rationale: Reflex tachycardia is not a typical adverse effect of alpha1- adrenergic blockers.
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