A patient diagnosed with rheumatoid arthritis is about to begin therapy with Etanercept, a tumor necrosis factor antagonist. The nurse anticipates the patient will be tested for
CYP450 genetic variants.
HLA-B genetic variants.
latent hepatitis B virus.
Blood type and crossmatch.
The Correct Answer is C
Choice A rationale: Testing for CYP450 genetic variants is more relevant for medications metabolized by the cytochrome P450 system.
Choice B rationale: HLA-B genetic variants are more associated with certain drug hypersensitivity reactions, not specifically for etanercept.
Choice C rationale: Etanercept can increase the risk of reactivating latent infections, including hepatitis B. Screening for latent hepatitis B virus is essential before starting therapy.
Choice D rationale: Blood type and crossmatch are not typically required for starting etanercept therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D"]
Explanation
Choice A rationale: Meperidine can cause respiratory depression, leading to shallow breathing.
Choice B rationale: Diarrhea is not a common effect of meperidine.
Choice C rationale: Meperidine can cause urinary retention.
Choice D rationale: Meperidine can cause hypotension.
Correct Answer is C
Explanation
Choice A rationale: 1500 mg is below the recommended maximum dose of acetaminophen.
Choice B rationale: 2000 mg is below the recommended maximum dose of acetaminophen.
Choice C rationale: The maximum recommended dose of acetaminophen in a 24-hour period is 4000 mg.
Choice D rationale: 5000 mg exceeds the recommended maximum dose of acetaminophen and can lead to liver damage.
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