A patient diagnosed with rheumatoid arthritis is about to begin therapy with Etanercept, a tumor necrosis factor antagonist. The nurse anticipates the patient will be tested for
CYP450 genetic variants.
HLA-B genetic variants.
latent hepatitis B virus.
Blood type and crossmatch.
The Correct Answer is C
Choice A rationale: Testing for CYP450 genetic variants is more relevant for medications metabolized by the cytochrome P450 system.
Choice B rationale: HLA-B genetic variants are more associated with certain drug hypersensitivity reactions, not specifically for etanercept.
Choice C rationale: Etanercept can increase the risk of reactivating latent infections, including hepatitis B. Screening for latent hepatitis B virus is essential before starting therapy.
Choice D rationale: Blood type and crossmatch are not typically required for starting etanercept therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale: Phenylephrine can help relieve nasal congestion and improve breathing.
Choice B rationale: Using the nasal spray as often as needed can lead to rebound congestion and should be avoided. Phenylephrine nasal spray should be used according to the healthcare provider's instructions.
Choice C rationale: Increasing oral fluids can help with hydration, especially when using a decongestant nasal spray.
Correct Answer is C
Explanation
Choice A rationale: Alendronate should be taken in the morning, not at bedtime, and the patient should remain upright for at least 30 minutes afterward to reduce the risk of esophageal irritation and ulceration.
Choice B rationale: Alendronate is often prescribed for longer durations, and the maximum duration is not typically limited to 1 to 2 years. The duration of treatment is individualized based on the patient's risk factors.
Choice C rationale: Alendronate should be taken while sitting upright with plenty of water to ensure proper esophageal transit and minimize the risk of irritation.
Choice D rationale: Alendronate should be taken with plain water, and taking it with coffee or orange juice is not recommended, as it may decrease absorption.
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