Exhibits
For each statement, click to indicate whether the statements by the student nurse indicate understanding or no understanding of naloxone. Each row must have one option selected.
"When given IV, naloxone starts working immediately and can last several hours."
"If the first dose does not work, you can give as many doses as needed to reverse respiratory depression."
"Naloxone will not affect the client's level of pain."
"You can give naloxone intravenously, intramuscularly, or subcutaneously."
"Naloxone works best on pure agonist opioids."
The Correct Answer is {"A":{"answers":"B"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"A"},"E":{"answers":"A"}}
- "When given IV, naloxone starts working immediately and can last several hours.": Although naloxone acts rapidly when given intravenously, its duration of action is relatively short—usually 30 to 90 minutes. Because naloxone’s effects may wear off before the opioid is fully cleared, repeated dosing and close monitoring are essential to prevent recurrence of respiratory depression.
- "If the first dose does not work, you can give as many doses as needed to reverse respiratory depression.": Naloxone dosing can be repeated safely as needed to reverse opioid-induced respiratory depression, especially with long-acting opioids. Proper titration minimizes risk of precipitated withdrawal while ensuring airway safety.
- "Naloxone will not affect the client's level of pain.": This statement shows lack of understanding since naloxone reverses opioid effects including analgesia. Administering naloxone can precipitate acute pain and withdrawal symptoms in opioid-dependent clients by blocking opioid receptors.
- "You can give naloxone intravenously, intramuscularly, or subcutaneously.": Naloxone is versatile and can be administered through various routes IV, IM, SC, and intranasally depending on clinical circumstances and urgency.
- "Naloxone works best on pure agonist opioids.": Naloxone effectively reverses respiratory and CNS depression caused by pure opioid agonists like morphine and fentanyl. Its effectiveness is reduced with mixed agonist-antagonists or partial agonists due to receptor affinity differences.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Check amount of drainage from each eye: Pilocarpine does not work by reducing eye drainage output in a way that would be measured externally. While increased aqueous humor outflow occurs internally, visible drainage from the eye is not an indicator of effectiveness.
B. Use Snellen chart to assess visual acuity: Although visual acuity can improve if intraocular pressure is reduced, changes are often minimal. The main goal in open-angle glaucoma management is to preserve vision by lowering intraocular pressure.
C. Review eye pressure measurements: Pilocarpine reduces intraocular pressure by contracting the ciliary muscle and increasing aqueous humor outflow through the trabecular meshwork. Monitoring intraocular pressure is the most accurate way to evaluate the drug’s effectiveness.
D. Palpate eyelids for decreased swelling: Eyelid swelling is not a primary symptom of open-angle glaucoma, nor is it an expected indicator of pilocarpine’s therapeutic action. Palpation of the eyelids would not provide meaningful information about drug efficacy.
Correct Answer is {"dropdown-group-1":"C","dropdown-group-2":"A","dropdown-group-3":"C"}
Explanation
Non opioid analgesic: Morphine is not a non-opioid analgesic; drugs in this category, like acetaminophen or NSAIDs, work through different pathways and do not bind opioid receptors.
Partial opioid agonist: Partial opioid agonists activate opioid receptors but with limited effect, often producing less analgesia and sometimes antagonistic effects. Morphine fully activates opioid receptors, producing stronger effects.
Pure opioid agonist: Morphine is a pure opioid agonist, meaning it fully stimulates opioid receptors, especially mu receptors, resulting in potent analgesia, sedation, and respiratory depression.
Mu: Morphine primarily activates mu opioid receptors, which are responsible for pain relief, sedation, euphoria, and respiratory depression. These receptors are the main targets for opioid analgesia.
Dopamine: Dopamine receptors regulate reward, motivation, and motor function. Morphine does not directly activate dopamine receptors as part of its mechanism for pain relief.
Muscarinic: Muscarinic receptors are involved in parasympathetic nervous system functions. Morphine does not act directly on these receptors for analgesic effects.
Chronic neuropathic pain: While morphine may be used in some chronic pain situations, neuropathic pain often responds better to other medications such as anticonvulsants or antidepressants due to differing pain mechanisms.
Mild inflammatory pain: Mild inflammatory pain is usually treated with non-opioid analgesics like NSAIDs. Morphine is generally reserved for moderate to severe pain levels.
Acute postoperative pain: Morphine is commonly used to manage acute postoperative pain because of its strong analgesic properties effective against nociceptive pain caused by surgery or injury.
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