In which part of the gastrointestinal tract does intrinsic factor bind to vitamin B12?
Ileum
Jejunum
Stomach
Duodenum
The Correct Answer is C
A. Ileum: This is the site of absorption, but the binding happens much earlier.
B. Jejunum: The complex simply travels through the jejunum.
C. Stomach: Intrinsic factor is secreted by the parietal cells of the stomach and binds to Vitamin B12 right there in the gastric environment.
D. Duodenum: While B12 is released from food proteins in the stomach and further processed in the duodenum, the initial secretion and binding of intrinsic factor begins in the stomach.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. It enhances the metabolism of vitamin B12: Intrinsic factor is strictly for transport and absorption, not metabolism in the liver.
B. It leads to decreased absorption of vitamin B12, causing deficiency: Vitamin B12 cannot cross the intestinal lining in the ileum on its own; it must be bound to intrinsic factor to be recognized and absorbed.
C. It boosts the storage of vitamin B12 in muscle tissues: B12 is primarily stored in the liver, and intrinsic factor does not affect storage mechanisms.
D. It increases the excretion of vitamin B12 through urine: If B12 isn't absorbed, it is excreted in the stool, not the urine.
Correct Answer is ["10"]
Explanation
Desired /Available× Volume = x
50mg/5mg× 1ml = 10 ml
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