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A patient presents with pernicious anemia. Which of the following is likely deficient?

A.

Folic acid

B.

Intrinsic factor

C.

Vitamin D

D.

Iron

Answer and Explanation

The Correct Answer is B

A. Folic acid: Folic acid deficiency causes a similar type of macrocytic anemia, but "pernicious anemia" specifically refers to the autoimmune loss of intrinsic factor.

B. Intrinsic factor: Pernicious anemia is an autoimmune condition where the body attacks parietal cells in the stomach, leading to a lack of intrinsic factor, which is required for Vitamin B12 absorption.

C. Vitamin D: Vitamin D is related to calcium absorption and bone health; its deficiency does not cause pernicious anemia.

D. Iron: Iron deficiency causes microcytic anemia, whereas pernicious anemia is a macrocytic (megaloblastic) anemia.


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Related Questions

Correct Answer is ["2"]

Explanation

Desired /Available= x

1400mg/700mg= 2 tablets

Correct Answer is A

Explanation

A. Vitamin B12: This is the specific vitamin that requires intrinsic factor (produced in the stomach) for absorption in the ileum.

B. Vitamin K: Vitamin K is synthesized by gut bacteria and absorbed with fats.

C. Vitamin C: Vitamin C is water-soluble and does not require intrinsic factor.

D. Vitamin A: Vitamin A is fat-soluble and does not require intrinsic factor.

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