Main defect in Potter Syndrome
Tubular necrosis
Renal hyperplasia
Renal failure
Renal metaplasia
The Correct Answer is C
A. Tubular necrosis: Tubular necrosis refers to the death of tubular epithelial cells in the kidneys, commonly due to ischemia or toxins. This is not the primary defect in Potter syndrome, which involves developmental abnormalities rather than acute tubular injury.
B. Renal hyperplasia: Hyperplasia means increased cell number leading to organ enlargement. Potter syndrome typically involves renal hypoplasia or agenesis rather than hyperplasia, so this is not consistent with the syndrome’s defect.
C. Renal failure: Potter syndrome primarily results from bilateral renal agenesis or severe renal dysplasia, leading to absent or nonfunctional kidneys and subsequent renal failure. The lack of functional kidneys leads to oligohydramnios and the characteristic features of Potter syndrome.
D. Renal metaplasia: Metaplasia refers to abnormal transformation of one differentiated tissue type into another. This process is not the main defect in Potter syndrome, which is related to kidney development failure rather than abnormal tissue differentiation.
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Related Questions
Correct Answer is B
Explanation
A. Atrophy of the remaining kidney: In cases of unilateral kidney loss, the remaining kidney typically does not atrophy but instead adapts to compensate for the lost function. Atrophy would be unlikely unless there is an underlying disease affecting the remaining kidney.
B. Compensatory hypertrophy of the remaining kidney: When one kidney is removed or nonfunctional, the remaining kidney often undergoes compensatory hypertrophy, increasing in size and function to handle the body's metabolic needs. This process helps maintain adequate renal function despite loss of one kidney.
C. Renal failure: While loss of one kidney reduces overall renal mass, a healthy remaining kidney usually compensates sufficiently to prevent renal failure. Renal failure is unlikely unless the remaining kidney has preexisting damage or disease.
D. Dysplasia in the remaining kidney: Dysplasia refers to abnormal development or growth of tissue, typically congenital. It is not an expected response to removal of the opposite kidney. The remaining kidney usually develops normally unless affected by a congenital abnormality.
Correct Answer is D
Explanation
A. High fiber diet, laxatives, increased water intake, increased reflex for defecation: These factors promote healthy bowel movements. Fiber adds bulk to stool, water softens it, laxatives stimulate movement, and an intact defecation reflex supports regular elimination, all of which prevent constipation.
B. Decreased fiber diet, decreased water intake, decreased reflex for defecation: These are contributing factors to constipation. However, it leaves out other significant causes like medications and medical conditions that impair bowel function.
C. Increased fiber diet, increased hydration, increased reflex for defecation, medications, absence of disease processes: Fiber, hydration, absence of disease and a strong reflex help prevent constipation. However, medications like opioids and anticholinergics often cause constipation regardless of diet and hydration.
D. Decreased fiber diet, decreased hydration, decreased reflex for defecation, medications, disease processes: A low-fiber diet and poor hydration lead to hard stools. A weak defecation reflex can result from neurological decline. Medications and chronic diseases such as diabetes or hypothyroidism can slow intestinal motility.
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