Which of the following are the correct statements? (Select all that apply)
Renal agenesis: failure of an organ (renal) to develop
Renal hypoplasia: failure of kidney to develop to normal size and contains fewer renal lobes
Renal dysgenesis: failure of an organ (kidney to develop normally)
Renal dysgenesis: failure of an organ (kidney) to develop
Correct Answer : A,B,C
A. Renal agenesis: failure of an organ (renal) to develop: Renal agenesis is the complete absence of one or both kidneys due to failure of development during fetal life. Bilateral agenesis is often fatal, while unilateral agenesis can be asymptomatic if the remaining kidney functions well.
B. Renal hypoplasia: failure of kidney to develop to normal size and contains fewer renal lobes: In renal hypoplasia, the kidney is structurally normal but smaller than average and contains fewer nephrons or lobes. This congenital condition may be unilateral and asymptomatic or bilateral and lead to renal insufficiency.
C. Renal dysgenesis: failure of an organ (kidney) to develop normally: Renal dysgenesis refers to abnormal development of the kidney structure, resulting in malformations that can impair function. It often involves malformed or nonfunctional renal tissue.
D. Renal dysgenesis: failure of an organ (kidney) to develop: This description better defines renal agenesis rather than dysgenesis, which implies abnormal rather than absent development.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Bruton's disorder: Also known as X-linked agammaglobulinemia, this is a primary immunodeficiency that results in absent or reduced B cells and recurrent bacterial infections. It does not involve distinct facial features or limb defects as described in the question.
B. SCID: Severe Combined Immunodeficiency involves profound defects in both B and T lymphocyte function, leading to severe infections early in life. It is not associated with the described craniofacial abnormalities or limb deformities.
C. Potter syndrome: This condition is caused by severe oligohydramnios, often due to bilateral renal agenesis, and leads to characteristic physical features including widely spaced eyes with epicanthic folds, low-set ears, a broad or beaked nose, a receding chin, and limb deformities.
D. Down Syndrome: While individuals with Down Syndrome often have characteristic facial features such as upslanting palpebral fissures, flat nasal bridges, and low-set ears, they typically do not have beak-like noses, receding chins, or limb defects in the way described.
Correct Answer is C
Explanation
A. Androgens (sex hormones): These are produced in the zona reticularis of the adrenal cortex. They contribute to the development of secondary sex characteristics and have a minor role compared to gonadal hormones.
B. Glucocorticoids (cortisol): Cortisol is synthesized in the zona fasciculata of the adrenal cortex. It regulates metabolism, immune responses, and the stress response, making it a key adrenal cortical hormone.
C. Epinephrine: This hormone is produced by the adrenal medulla, not the cortex. It plays a major role in the fight-or-flight response, increasing heart rate and blood glucose levels during stress.
D. Mineralocorticoids (aldosterone): Aldosterone is produced in the zona glomerulosa of the adrenal cortex. It is essential for sodium retention, potassium excretion, and blood pressure regulation.
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