What is the key difference between primary and secondary endocrine disorders?

Primary disorders affect hormone receptors, while secondary disorders affect hormone production

Primary disorders originate in the target organ, while secondary disorders originate in the pituitary gland or hypothalamus

Primary disorders involve the hypothalamus, while secondary disorders involve the target organ

Primary disorders are caused by external factors, while secondary disorders are caused by genetic mutations

Answer and Explanation

The Correct Answer is B

A. Primary disorders affect hormone receptors, while secondary disorders affect hormone production: While receptor sensitivity may play a role in some conditions, the main distinction between primary and secondary endocrine disorders is based on the location of dysfunction, not receptor or hormone function alone.

B. Primary disorders originate in the target organ, while secondary disorders originate in the pituitary gland or hypothalamus: In primary disorders, the problem lies in the endocrine gland itself (e.g., the thyroid gland in primary hypothyroidism), while secondary disorders result from dysfunction in regulatory centers like the pituitary or hypothalamus.

C. Primary disorders involve the hypothalamus, while secondary disorders involve the target organ: This reverses the correct relationship. Secondary disorders typically involve the hypothalamus or pituitary, not primary disorders.

D. Primary disorders are caused by external factors, while secondary disorders are caused by genetic mutations: While both external and genetic factors can contribute to endocrine disorders, this distinction does not define the difference between primary and secondary types. The classification is based on the anatomical source of dysfunction.

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Correct Answer is A

Explanation

A. Decision-making, problem-solving, and planning: The frontal lobe is primarily responsible for higher-order executive functions such as reasoning, decision-making, problem-solving, judgment, and planning. It also plays a role in personality and voluntary motor control, especially through the prefrontal cortex and motor areas.

B. Vision and color recognition: These functions are associated with the occipital lobe, which is located at the back of the brain and specializes in processing visual input, including aspects like color, shape, and motion.

C. Language comprehension and memory: Language comprehension is primarily controlled by Wernicke’s area, which is located in the temporal lobe. Memory is also associated with the temporal lobe and the limbic system structures like the hippocampus.

D. Movement coordination and balance: These are functions of the cerebellum, which regulates fine motor control, coordination, balance, and posture—not the frontal lobe.

A. Brain, blood, cerebrospinal fluid (CSF) B. Cerebrospinal fluid (CSF), blood, oxygen C. Brain, cerebrospinal fluid (CSF), air D. Brain, blood, lymphatic fluid

Correct Answer is A

Explanation

A. Brain, blood, cerebrospinal fluid (CSF): These are the three main components within the cranial vault as described by the Monro-Kellie doctrine. The total volume of these components remains constant, and any increase in one must be offset by a decrease in another to prevent elevated ICP.

B. Cerebrospinal fluid (CSF), blood, oxygen: While CSF and blood are intracranial components, oxygen is not a physical substance occupying volume in the cranial cavity. It is transported within the blood and does not contribute to changes in ICP in terms of physical space.

C. Brain, cerebrospinal fluid (CSF), air: Air is not a normal component of the cranial cavity. The presence of air would indicate pathology, such as a skull fracture with pneumocephalus, which is abnormal and can contribute to increased ICP but is not a standard component.

D. Brain, blood, lymphatic fluid: While the brain and blood are correct components, the central nervous system, including the brain, does not have a conventional lymphatic system like other parts of the body. Waste products are primarily cleared by the glymphatic system, which utilizes CSF, rather than traditional lymphatic fluid.

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What is the key difference between primary and secondary endocrine disorders?

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Correct Answer is A

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