Rheumatic fever is believed to be an uncommon complication of an acute infection with which of the following microorganisms?

Which of the following pathologic findings is best described as a collection of platelets, fibrin, and entrapped cellular elements that is attached to the luminal surface of an artery or vein?

A 64-year-old woman with bilateral. varicose veins of her legs developed sudden onset\ chest pain. and expectorated blood the next day (hemoptysis). What could have caused the patient’s symptoms?

A 68-year-old male with a history of severe COPD presents to the emergency department with acute onset dyspnea, tachypnea, peripheral edema, and jugular venous distention. He reports worsening fatigue and shortness of breath over several weeks, now occurring at rest. Physical exam reveals cyanosis, a loud P2 heart sound, and hepatomegaly. An echocardiogram demonstrates right ventricular dilation with right ventricular hypertrophy and reduced right ventricular systolic function. Which of the following is the most likely diagnosis?

A 68-year-old woman is admitted to the hospital with a chief complaint of substernal chest pain. Examination reveals an obese woman (BMI -32 kg/m2) with a long history of angina pectoris and intermittent claudication (leg cramps). Which of the following is the most likely underlying disease process in this patient?

A 58-year-old woman with varicose veins of her legs asks you about the pathogenesis and complications of deep venous thrombosis (DVT). Which of the following is a potentially fatal complication of deep venous thrombosis?

A 55-year-old man with polycystic kidney disease dies in renal failure (uremia). A shaggy exudate on the surface of this heart is observed at autopsy (shown). This inflammatory exudate contains large amounts of which of the following plasma-derived proteins?

A 32-year-old woman who weighs 125 kg (275 lb) is in the hospital for open reduction and internal fixation of a fractured ankle. She states that the only medication she is taking is an oral contraceptive. Four days after the surgery, she suddenly complains of chest pain and is noted to have difficulty breathing. Pulse oximetry reveals an arterial pO2 of 75%. She becomes unresponsive. During resuscitation, she is noted to have pulseless electrical activity. Despite aggressive efforts, she dies. An autopsy is most likely to reveal which of the following conditions?

Autopsy of an 80-year-old woman with a history of congestive heart failure reveals marked enlargement of the left ventricle. Which of the following mechanisms of disease is most likely responsible for this autopsy finding?

A sputum sample obtained from a 68-year-old former construction worker reveals needle-like inert minerals (shown). This patient is at increased risk of developing which of the following malignant neoplasms?

A 67-year-old man presents to your office with worsening cough, sputum production, and shortness of breath. He has been a cigarette smoker for the past 50 years, smoking approximately 1 pack a day. He has a chronic AM cough productive of some yellow sputum but generally feels okay during the day. He was in his usual state of health until two weeks ago when he developed a cold. Since then, he has had a hacking cough and increased thick sputum production. He also has had difficulty walking more than a block without stopping due to shortness of breath. Physical examination reveals prolonged expiration, audible wheezing, and diffuse rhonchi throughout both lung fields. Chest x-ray shows hyperinflation of both lungs with a flattened diaphragm. His most likely diagnosis is: