(Select all that apply) A client is receiving vancomycin (Vancocin) for a severe infection caused by methicillin-resistant Staphylococcus aureus (MRSA).
The nurse monitors the client for signs of nephrotoxicity, which include:
Elevated serum creatinine
Decreased urine output
Increased blood pressure
Hematuria
Tinnitus.
Correct Answer : A,B
Elevated serum creatinine and decreased urine output are signs of nephrotoxicity, which is a potential adverse effect of vancomycin (Vancocin) therapy. Nephrotoxicity is damage to the kidneys caused by toxic substances.
Choice C is wrong because increased blood pressure is not a sign of nephrotoxicity. Hypotension may occur during vancomycin infusion, especially if it is given too rapidly.
Choice D is wrong because hematuria is not a sign of nephrotoxicity.
Hematuria is blood in the urine, which may indicate other problems such as urinary tract infection, kidney stones, or bladder cancer.
Choice E is wrong because tinnitus is not a sign of nephrotoxicity. Tinnitus is ringing or buzzing in the ears, which may indicate ototoxicity, another potential adverse effect of vancomycin therapy.
Ototoxicity is damage to the ears caused by toxic substances.
Normal ranges for serum creatinine are 0.6 to 1.2 mg/dL for men and 0.5 to 1.1 mg/dL for women.
Normal ranges for urine output are 800 to 2000 mL per day or 30 to 50 mL per hour.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
The patient should avoid alcohol while taking these drugs because alcohol can increase the risk of liver toxicity.These drugs are metabolized by the liver and can cause hepatotoxicity, especially isoniazid and pyrazinamide.The nurse should monitor the patient’s liver function tests and advise the patient to report any signs of liver damage, such as dark urine, fatigue, or jaundice.
Choice B is wrong because Grapefruit juice is wrong because grapefruit juice does not interact with these drugs.
Grapefruit juice can affect the metabolism of some other drugs, such as statins, calcium channel blockers, or cyclosporine, but not antitubercular drugs.
Choice C is wrong because Milk is wrong because milk does not interact with these drugs.
Milk can reduce the absorption of some other drugs, such as tetracyclines or fluoroquinolones, but not antitubercular drugs.
Choice D is wrong because Caffeine is wrong because caffeine does not interact with these drugs.
Caffeine can increase the effects of some other drugs, such as theophylline or clozapine, but not antitubercular drugs.
Correct Answer is ["A","B"]
Explanation
Elevated serum creatinine and decreased urine output are signs of nephrotoxicity, which is a potential adverse effect of vancomycin (Vancocin) therapy. Nephrotoxicity is damage to the kidneys caused by toxic substances.
Choice C is wrong because increased blood pressure is not a sign of nephrotoxicity.Hypotension may occur during vancomycin infusion, especially if it is given too rapidly.
Choice D is wrong because hematuria is not a sign of nephrotoxicity.
Hematuria is blood in the urine, which may indicate other problems such as urinary tract infection, kidney stones, or bladder cancer.
Choice E is wrong because tinnitus is not a sign of nephrotoxicity.Tinnitus is ringing or buzzing in the ears, which may indicate ototoxicity, another potential adverse effect of vancomycin therapy.
Ototoxicity is damage to the ears caused by toxic substances.
Normal ranges for serum creatinine are 0.6 to 1.2 mg/dL for men and 0.5 to 1.1 mg/dL for women.
Normal ranges for urine output are 800 to 2000 mL per day or 30 to 50 mL per hour.
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