The

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   secrete(s) a hormone as a response to hypocalcemia.

A. Insulin: insulin is a low-concentration peptide hormone (produced by pancreas), not the major plasma protein.
B. Bilirubin: bilirubin is a breakdown product of heme (not a protein) and is present in low concentrations.
C. Albumin: albumin is the most abundant plasma protein (produced by the liver); it maintains oncotic pressure and binds/ transports many substances.
D. Creatinine: creatinine is a small waste molecule (not a protein) present at low concentration.
E. Creatine: creatine is a small molecule involved in muscle energy storage, not a plasma protein.

A. slowly; slowly; widespread: The nervous system responds quickly, not slowly, and its effects are generally more specific/localized than widespread.
B. quickly; quickly; specific: The nervous system reacts quickly to stimuli (milliseconds to seconds), adapts quickly (e.g., rapid onset/offset, habituation), and produces specific targeted effects via precise neuronal pathways - contrasts with the endocrine system which is slower to start, slower to adapt, and often produces more widespread effects.
C. slowly; quickly; specific: The nervous system does not react slowly; it reacts quickly.
D. quickly; slowly; specific: While the nervous system reacts quickly, it typically adapts quickly, not slowly; endocrine responses adapt more slowly.
E. quickly; quickly; widespread: The nervous system is quick, but its effects are usually specific/local, not widespread - endocrine signaling is the one usually producing widespread effects.