The gastric secretion acid reducer class that ends in "dine" is:
Proton pump inhibitors
Antacids
Histamine-2 antagonists
Gastrointestinal Protectants
The Correct Answer is C
A. Proton pump inhibitors: Proton pump inhibitors (PPIs) typically end in "-prazole" (e.g., omeprazole, pantoprazole) and work by irreversibly inhibiting the hydrogen-potassium ATPase pump in gastric parietal cells.
B. Antacids: Antacids are compounds such as aluminum hydroxide or magnesium hydroxide that neutralize existing stomach acid on contact. They do not follow a naming pattern like "-dine" and act through physical-chemical interaction, not histamine receptor blockage.
C. Histamine-2 antagonists: Drugs in this class end in "-dine" (e.g., ranitidine, famotidine) and work by blocking histamine H2 receptors in the gastric parietal cells. This action reduces acid secretion and makes them effective in treating peptic ulcers and gastroesophageal reflux disease.
D. Gastrointestinal protectants: These agents, like sucralfate, form a protective barrier over gastric mucosa but do not reduce acid production directly. They also do not have names ending in "-dine" and serve a different therapeutic role by coating ulcers rather than inhibiting acid secretion.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. The client's bowel sounds are reduced: Decreased bowel sounds may indicate slowed intestinal motility, which is not a desired effect of psyllium. Normal or active bowel sounds would be more consistent with the therapeutic goal of increased peristalsis and bowel regularity.
B. The client remains free of diarrhea: Psyllium is a bulk-forming laxative that normalizes stool consistency. While avoiding diarrhea is beneficial, the absence of diarrhea alone does not confirm the medication is effectively treating constipation or achieving its full therapeutic effect.
C. The client has two to three bowel movements daily: While this frequency may be acceptable for some clients, it is not the primary therapeutic target of psyllium. Psyllium works by absorbing water and increasing stool bulk, and frequency can vary depending on individual bowel patterns.
D. The bulk of the client's stools is increased: Psyllium functions by forming a gel-like mass when mixed with water, which increases stool bulk and triggers peristalsis. This outcome directly reflects the expected therapeutic effect and is the best indicator that the medication is working properly.
Correct Answer is B
Explanation
A. Allergies: Although histamine is involved in allergic reactions, H2 antagonists target histamine receptors in the stomach, not the ones responsible for allergic symptoms. H1 blockers, such as diphenhydramine or loratadine, are used to manage allergies, not H2 antagonists.
B. Gastroesophageal Reflux Disease (GERD): Histamine-2 antagonists like ranitidine and famotidine reduce gastric acid secretion by blocking H2 receptors on parietal cells. This helps relieve symptoms of GERD, such as heartburn and acid regurgitation.
C. Constipation: Constipation is unrelated to histamine activity in the gastrointestinal tract. Treatment involves stool softeners, laxatives, or dietary fiber, not acid-suppressing agents like H2 blockers.
D. Diarrhea: H2 antagonists do not reduce intestinal motility or fluid secretion and have no therapeutic role in treating diarrhea. Antidiarrheal agents like loperamide are more appropriate for managing this condition.
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