The nurse has given 800mg of a medication that has an 8-hour half-life. How much of the medication will remain in the client's body 24 hours after administration if no additional medication is given?
50 mg
200 mg
100 mg
400 mg
The Correct Answer is C
A half-life is the time it takes for the concentration of a drug in the body to decrease by half. In this case, the medication has an 8-hour half-life, so after 8 hours, the concentration of the medication in the client's body would be reduced to 400mg (half of the initial dose of 800mg). After another 8 hours (16 hours total), the concentration would be reduced to 200mg. After another 8 hours (24 hours total), the concentration would be reduced to 100mg.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for several reasons, including reducing the risk of suicide with overdose ³. TCAs have a higher potential for serious or fatal toxicity when taken in large amounts compared to SSRIs ³.
Option A is incorrect because SSRIs can cause sexual dysfunction as a side effect.
Option B is incorrect because both SSRIs and TCAs can cause weight gain and gastrointestinal (GI) effects.
Option C is incorrect because SSRIs can increase the risk of serotonin syndrome when taken with other medications that affect serotonin levels.
Correct Answer is A
Explanation
Donepezil is a medication used to treat Alzheimer's dementia. Its main mechanism of action is the inhibition of the acetylcholinesterase enzyme in the brain ¹. This increases the availability of acetylcholine at cholinergic synapses ⁵, which can improve cognition and function in clients with Alzheimer's dementia ¹.
Option B is incorrect because donepezil does not decrease acetylcholine in the periphery to increase movement.
Option C is incorrect because donepezil does not delay the transmission of acetylcholine at the neuronal junction.
Option D is incorrect because donepezil does not bind dopamine at neuron receptor sites to increase ability.
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