The nurse initiates an infusion of piperacillin-tazobactam for a client with a urinary tract infection. Five minutes into the infusion, the client reports not feeling well. Which client manifestation should the nurse identify as a reason to stop the infusion?

Scratchy throat.

Pupillary constriction.

Hypertension.

Bradycardia.

None

Answer and Explanation

The Correct Answer is A

A. A scratchy throat can be an early sign of an allergic reaction to the antibiotic, which could progress to anaphylaxis if the infusion continues. Immediate cessation of the infusion is essential to prevent serious complications, and the nurse should notify the provider and initiate emergency interventions if needed.

B. Pupillary constriction is not a typical sign of an acute allergic reaction to piperacillin-tazobactam and does not warrant stopping the infusion.

C. Hypertension is not an expected early manifestation of an allergic reaction to this antibiotic. Blood pressure changes are more likely to occur later if anaphylaxis develops.

D. Bradycardia is not commonly associated with an early allergic reaction to antibiotics and does not require immediate cessation of the infusion unless other signs of anaphylaxis are present.

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Correct Answer is C

Explanation

Choice A rationale: Checking the capillary glucose level is not relevant to the observation of yellow skin color. Jaundice is related to liver function, not glucose levels.

Choice B rationale: Oxygen saturation measurement is not relevant to the observation of yellow skin color. It is used to assess the oxygen-carrying capacity of the blood, not liver function.

Choice C rationale: Yellow discoloration of the skin (jaundice) can be indicative of liver dysfunction or damage. Since the client takes acetaminophen for chronic pain, which is metabolized in the liver, the nurse should be concerned about potential hepatotoxicity. Reporting the findings to the healthcare provider is essential for further evaluation and management.

Choice D rationale: Reducing the medication dose is not appropriate without further evaluation and guidance from the healthcare provider. Jaundice may indicate liver dysfunction, and altering the medication without professional assessment could be unsafe.

A. Two hours after completion of the IV dose and two hours before the next administration of the medication. B. One hour after completion of the IV dose and one hour before the next administration of the medication. C. Thirty minutes into the administration of the IV dose and 30 minutes before the next administration of the medication. D. Immediately after completion of the IV dose and 30 minutes before the next administration of the medication. E. None F. None

Correct Answer is B

Explanation

choice A, Drawing the peak level two hours after the IV dose is too late to capture the drug's highest serum concentration. Similarly, drawing the trough two hours before the next dose does not reflect the lowest drug level accurately.
Choice B,Drawing the peak level one hour after completion of the IV dose ensures an accurate measurement of the highest serum concentration, as vancomycin typically peaks within this time frame. Drawing the trough one hour before the next dose ensures the lowest concentration of the drug is measured, providing precise therapeutic monitoring.

Choice C is incorrect because drawing blood 30 minutes into the IV dose would not allow the full dose to circulate and reach peak levels in the bloodstream.

Choice D.Drawing the peak level immediately after the completion of the IV dose is too early, as the drug needs time to distribute in the bloodstream and reach its highest concentration. While drawing the trough 30 minutes before the next dose is appropriate, the incorrect timing of the peak makes this option unsuitable.

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The nurse initiates an infusion of piperacillin-tazobactam for a client with a urinary tract infection. Five minutes into the infusion, the client reports not feeling well. Which client manifestation should the nurse identify as a reason to stop the infusion?

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Naxlex Comprehensive Predictor Exams

While assessing a client who takes acetaminophen for chronic pain, the nurse observes that the client's skin looks yellow in color. Which action should the nurse take in response to this finding?

Correct Answer is C

Explanation

A client is receiving intravenous (IV) vancomycin and the nurse plans to draw blood for a peak and trough to determine the serum level of the drug. Which collection times provide the best determination of these levels?

Correct Answer is B

Explanation

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