The patient/client is to receive 250 mg of cefazolin, IM, every 12 hours. The directions for reconstitution of cefazolin for injection are on the drug label in the form of a table. Directions read: “Use 2 mL of sterile water as a diluent. Resulting solution contains approximately 125 mg/mL with an approximate available volume of 2 mL.” What is the final concentration of the prepared cefazolin solution for IM administration?
125 mg/ml.
100 mg/1.5 ml.
50 mg/1.5 mL
150 mg/mL
The Correct Answer is A
A. 125 mg/mL: The reconstitution directions explicitly state: "Resulting solution contains approximately 125 mg/mL." Concentration is the amount of drug per unit of volume (mg/mL). The question asks for the final concentration, which is given directly in the label instructions.
B. 100 mg/1.5 mL: This value is likely a result of misinterpreting the available volume or the total drug content in the vial.
C. 50 mg/1.5 mL: This is an incorrect concentration and represents a much weaker solution than what the label states.
D. 150 mg/mL: While it is close to the given concentration, the nurse must always use the concentration explicitly stated on the drug label for accurate dosing, which is 125mg/mL.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","D","E"]
Explanation
A. Use the Z-track method only in the deltoid site:The Z-track method is most often used in the large muscles of the buttock (ventrogluteal) or the thigh (vastus lateralis), not the small deltoid muscle, which can only safely accommodate small volumes.
B. Quickly remove the needle after injecting the medication:After injecting the medication, the needle should be removed quickly and smoothly, and the skin released to allow the muscle layers to slide back over the injection track, effectively sealing the medication within the muscle.
C. Allow the skin to return to its original position slowly while removing the needle:The skin is laterally displaced (pulled) before insertion.It should be held taut until after the needle is removed and the dose is delivered. Releasing it slowly while removing the needle would allow the drug to escape.
D. Do not massage the injection site:Massaging the site is contraindicated as it could force the medication out of the muscle, allowing it to leak into the subcutaneous tissue and negate the benefit of the Z-track seal.
E. Insert the needle at 90 degrees and inject the medication:The Z-track method is for deep intramuscular (IM) injections, which are administered at a 90-degree angle to ensure the medication reaches the muscle tissue.
F. Pinch the skin of the injection site to raise the site:The skin should be pulled or displaced laterally (tautly) rather than pinched, to create the "Z" or zigzag path that locks the medication in place.5Pinching is used for subcutaneous injections.
Correct Answer is D
Explanation
Ordered dose: 120 mg IM.
Available concentration: 50 mg per mL.
Volume needed = 120 ÷ 50 = 2.4 mL per dose.
Correct answer: 2.4 mL/dose.
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