To which of the following therapeutic drug classes does oxycodone hydrochloride belong?
Antiemetic
Opioid Analgesic
Antibiotic
Laxative
The Correct Answer is B
A. Antiemetic agents typically antagonize dopamine or serotonin receptors to prevent emesis. Oxycodone actually causes nausea and vomiting by stimulating the chemoreceptor trigger zone. It is not classified as an antiemetic drug in any medical context or pharmacopeia.
B. Opioid analgesic is the correct therapeutic class for oxycodone hydrochloride. It acts as a full agonist at mu-opioid receptors within the central nervous system. This interaction inhibits ascending pain pathways and alters the perception of and response to pain.
C. Antibiotic medications target bacterial structures like cell walls or ribosomes to treat infections. Oxycodone possesses no antimicrobial activity against prokaryotic or eukaryotic pathogens. It is a semi-synthetic derivative of the alkaloid thebaine, not a metabolic product of microorganisms.
D. Laxative agents promote defecation by increasing stool bulk or stimulating intestinal peristalsis. Oxycodone hydrochloride is well-known for causing significant constipation by decreasing gastrointestinal motility. This occurs through the activation of mu-opioid receptors in the myenteric plexus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Conjunctivitis is an inflammatory or infectious process of the conjunctiva requiring antibiotics or antihistamines. Latanoprost does not possess antimicrobial or antiallergic properties. It is not indicated for the management of surface ocular infections or redness.
B. Ocular inflammation is typically treated with topical corticosteroids or nonsteroidal anti-inflammatory drugs to inhibit arachidonic acid metabolites. Latanoprost is a prostaglandin F2-alpha analogue and does not reduce inflammatory cascades. It is not approved for uveitis or post-surgical inflammation.
C. Elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension is the primary indication. Latanoprost increases the uveoscleral outflow of aqueous humor by remodeling the extracellular matrix. This physiological shift effectively reduces the internal pressure of the eye.
D. Closed-angle glaucoma is a medical emergency that often requires surgical intervention or different pharmacological mechanisms. Latanoprost is specifically labeled for open-angle glaucoma where the drainage angle remains physically open. It is not the standard primary treatment for acute angle-closure.
Correct Answer is C
Explanation
A. Focalin is the brand name for dexmethylphenidate, which is the d-threo-enantiomer of methylphenidate. It acts primarily as a dopamine and norepinephrine reuptake inhibitor. It does not contain the sulfate or saccharate salts of the amphetamine molecule found in the question.
B. Vyvanse contains lisdexamfetamine dimesylate, a prodrug converted to dextroamphetamine in the blood. While it provides dextroamphetamine, it is a single-molecule formulation rather than a mixture of salts. It lacks the levoamphetamine component found in the mixed salt combination.
C. Adderall is the proprietary name for a combination of 4 different amphetamine salts. It specifically consists of dextroamphetamine saccharate, dextroamphetamine sulfate, amphetamine aspartate monohydrate, and amphetamine sulfate. This mixture provides a specific ratio of 3 to 1 dextroamphetamine to levoamphetamine.
D. Ritalin is the brand name for methylphenidate hydrochloride, a central nervous system stimulant. Its mechanism involves the inhibition of the dopamine transporter and norepinephrine transporter. It is chemically distinct from the phenethylamine derivatives found in amphetamine and dextroamphetamine salt mixtures.
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