What is the brand name for diclofenac sodium?
Advil
Voltaren
Naprosyn
Toradol
The Correct Answer is B
A. Advil is the proprietary brand name for ibuprofen, a propionic acid derivative. It functions by non-selectively inhibiting cyclooxygenase 1 and 2 enzymes. It is chemically distinct from the phenylacetic acid derivative requested in the question stem.
B. Voltaren is the brand name for diclofenac sodium, a non-steroidal anti-inflammatory drug. It inhibits prostaglandin synthesis by targeting the cyclooxygenase pathway. This specific brand is commonly available in oral, topical, and ophthalmic formulations for pain management.
C. Naprosyn is the brand name for naproxen, another member of the propionic acid class of non-steroidal anti-inflammatory drugs. It provides analgesic and anti-inflammatory effects through systemic enzyme inhibition. It is not the brand name for diclofenac sodium.
D. Toradol is the brand name for ketorolac tromethamine, a potent heterocyclic acetic acid derivative. It is primarily used for short-term management of moderately severe acute pain. It represents a different chemical entity than the diclofenac molecule specified.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Conjunctivitis is an inflammatory or infectious process of the conjunctiva requiring antibiotics or antihistamines. Latanoprost does not possess antimicrobial or antiallergic properties. It is not indicated for the management of surface ocular infections or redness.
B. Ocular inflammation is typically treated with topical corticosteroids or nonsteroidal anti-inflammatory drugs to inhibit arachidonic acid metabolites. Latanoprost is a prostaglandin F2-alpha analogue and does not reduce inflammatory cascades. It is not approved for uveitis or post-surgical inflammation.
C. Elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension is the primary indication. Latanoprost increases the uveoscleral outflow of aqueous humor by remodeling the extracellular matrix. This physiological shift effectively reduces the internal pressure of the eye.
D. Closed-angle glaucoma is a medical emergency that often requires surgical intervention or different pharmacological mechanisms. Latanoprost is specifically labeled for open-angle glaucoma where the drainage angle remains physically open. It is not the standard primary treatment for acute angle-closure.
Correct Answer is C
Explanation
A. Rizatriptan is the active pharmaceutical ingredient for the brand Maxalt. While it belongs to the same selective 5-hydroxytryptamine 1B and 1D receptor agonist class, it is not the chemical constituent of Imitrex. It possesses a different pharmacokinetic profile.
B. Almotriptan is the generic name for the brand Axert. This compound is indicated for the acute treatment of migraine with or without aura in adults. It is a separate molecular entity from the drug requested in the question stem.
C. Sumatriptan is the generic name for Imitrex, the first triptan developed for clinical use. It acts as a selective agonist at vascular 5-HT1B and 5-HT1D receptors. This binding induces cranial vessel vasoconstriction and inhibits the release of proinflammatory neuropeptides.
D. Eletriptan is marketed under the brand name Relpax. It is a second-generation triptan used for migraine abortive therapy. It is not the active ingredient in Imitrex. Its metabolism and bioavailability differ significantly from those of sumatriptan.
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