What is the brand name of celecoxib?
MS Contin
Voltaren
Celebrex
Motrin
The Correct Answer is C
A. MS Contin is the brand name for morphine sulfate extended-release, a potent opioid analgesic. It functions as a pure mu-opioid receptor agonist to modulate the perception of pain. It is not chemically related to the sulfonamide-derived compound celecoxib.
B. Voltaren is the brand name for diclofenac, a non-selective nonsteroidal anti-inflammatory drug. It inhibits both cyclooxygenase-1 and cyclooxygenase-2 enzymes to reduce prostaglandin synthesis. Celecoxib is a distinct pharmaceutical agent with a different selectivity profile than diclofenac.
C. Celebrex is the brand name for celecoxib, a selective cyclooxygenase-2 inhibitor. It primarily targets the inducible isoform of the cyclooxygenase enzyme to decrease inflammatory prostaglandin production. This specificity reduces the incidence of gastrointestinal toxicity compared to non-selective agents.
D. Motrin is the brand name for ibuprofen, a propionic acid derivative and non-selective nonsteroidal anti-inflammatory drug. It provides analgesic and antipyretic effects by inhibiting both cyclooxygenase isoforms. It is not the proprietary name for the selective inhibitor celecoxib.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Avelox is the proprietary brand name for moxifloxacin, a fourth-generation fluoroquinolone. While it shares the same pharmacological class as ciprofloxacin, its chemical structure contains a methoxy group for improved gram-positive activity. It is not the brand name for ciprofloxacin.
B. Augmentin is a combination of amoxicillin and clavulanate potassium, representing a beta-lactam antibiotic and a beta-lactamase inhibitor. It targets bacterial cell wall synthesis rather than DNA gyrase. This medication is chemically and mechanistically distinct from the fluoroquinolone class.
C. Cipro is the brand name for ciprofloxacin, a second-generation fluoroquinolone. It functions by inhibiting bacterial DNA gyrase and topoisomerase 4, which are essential for DNA replication. This mechanism provides potent bactericidal activity against a wide range of aerobic pathogens.
D. Levaquin is the brand name for levofloxacin, the S-enantiomer of the racemic mixture ofloxacin. It is a third-generation fluoroquinolone with a broader spectrum of activity against respiratory pathogens than ciprofloxacin. It is a separate pharmaceutical product from ciprofloxacin hydrochloride.
Correct Answer is B
Explanation
A. Proventil is a proprietary brand name for albuterol sulfate, a short-acting beta-2 adrenergic agonist. It is clinically indicated for the relief of bronchospasm in patients with reversible obstructive airway disease. It lacks any antihistaminic or antiemetic properties.
B. Phenergan is the brand name for promethazine hydrochloride, a phenothiazine derivative. It functions as a non-selective antagonist at central and peripheral H1 receptors. This molecule possesses significant antiemetic, sedative, and anticholinergic properties used in various clinical settings.
C. Pulmicort is the brand name for budesonide, an inhaled corticosteroid used for the maintenance treatment of asthma. It modulates the inflammatory response by reducing the recruitment of inflammatory cells. It is not chemically related to the drug promethazine.
D. Proair is another brand name for albuterol sulfate, similar to Proventil. It is administered via metered-dose inhaler for the acute management of asthma symptoms. It does not contain promethazine hydrochloride and targets adrenergic rather than histaminergic receptor pathways.
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