What is the brand name of clobetasol propionate (topical)?
Temovate
Neomycin
Nystatin
Neosporin
The Correct Answer is A
A. Temovate is the proprietary brand name for clobetasol propionate, a super-high potency topical corticosteroid. It induces phospholipase A2 inhibitory proteins, known as lipocortins, which control the biosynthesis of potent inflammatory mediators. This reduces cutaneous inflammation and pruritus.
B. Neomycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It is not the brand name for clobetasol propionate. It is commonly used for topical prophylaxis against minor skin infections.
C. Nystatin is a polyene antifungal agent used to treat cutaneous or mucocutaneous candidiasis. It binds to ergosterol in the fungal cell membrane, creating pores that lead to the leakage of intracellular components. It is not associated with clobetasol.
D. Neosporin is a brand name for a triple antibiotic combination containing neomycin, polymyxin B, and bacitracin. It is used for the prevention of infection in minor wounds and lacks corticosteroid activity. It does not contain the ingredient clobetasol.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Zanaflex is the brand name for tizanidine, a central alpha-2 adrenergic agonist. It reduces spasticity by increasing presynaptic inhibition of motor neurons within the spinal cord. It is pharmacologically distinct from the carbamate derivative specified in the question stem.
B. Lioresal is the proprietary name for baclofen, which acts as a gamma-aminobutyric acid-B receptor agonist. It is primarily indicated for the management of spasticity resulting from multiple sclerosis or spinal cord injuries. It is not the brand for methocarbamol.
C. Amrix is the brand name for the extended-release formulation of cyclobenzaprine hydrochloride. It functions as a skeletal muscle relaxant by acting on the brainstem to reduce tonic somatic motor activity. It is not the proprietary name for methocarbamol.
D. Robaxin is the brand name for methocarbamol, a central nervous system depressant with sedative and skeletal muscle relaxant properties. It inhibits polysynaptic reflex pathways in the spinal cord and subcortical areas. This medication is indicated for musculoskeletal pain relief.
Correct Answer is B
Explanation
A. Albuterol sulfate is a short-acting beta-2 agonist while tiotropium bromide is a long-acting muscarinic antagonist. This specific combination is not marketed under the brand Advair. It is typically used for separate bronchodilatory pathways in chronic obstructive pulmonary disease.
B. Advair is the brand name for the combination of fluticasone propionate and salmeterol xinafoate. Fluticasone is a potent corticosteroid that reduces airway inflammation. Salmeterol is a long-acting beta-2 adrenergic agonist that maintains bronchodilation through cyclic adenosine monophosphate.
C. Budesonide and formoterol fumarate dihydrate represent the generic components of the brand Symbicort. While it contains a corticosteroid and a long-acting beta-2 agonist, it is a different molecular entity. It is not the generic name for Advair.
D. Albuterol sulfate and ipratropium bromide are the active ingredients in the brand Combivent or DuoNeb. This mixture combines a short-acting beta-2 agonist with a short-acting muscarinic antagonist. It is not associated with the proprietary name Advair.
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