What is the brand name of lidocaine (transdermal)?
Lidoderm
Actos
Lithobid
Dilantin
The Correct Answer is A
A. Lidoderm is the brand name for the 5 percent transdermal patch containing lidocaine. It functions as a local anesthetic by blocking voltage-gated sodium channels in neuronal membranes. This stabilizes the membrane and inhibits the initiation and conduction of nociceptive nerve impulses.
B. Actos is the proprietary brand name for pioglitazone, a thiazolidinedione used in type 2 diabetes mellitus. It acts as an agonist for the peroxisome proliferator-activated receptor gamma to improve insulin sensitivity. It is pharmacologically unrelated to transdermal lidocaine preparations.
C. Lithobid is the brand name for a slow-release formulation of lithium carbonate. It is used primarily as a mood stabilizer in the management of bipolar disorder. It modulates neurotransmission via various intracellular signaling pathways and is not a local anesthetic.
D. Dilantin is the brand name for phenytoin, a hydantoin derivative used as an antiepileptic medication. It stabilizes neuronal membranes by promoting sodium efflux or decreasing sodium influx during generation of nerve impulses. It is not the brand name for lidocaine.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Hydromorphone HCl does not act directly on the motor end plate or the spinal cord to reduce skeletal muscle tone. It is not classified as a spasmolytic or neuromuscular blocker. Its primary therapeutic indication is not the relief of muscle spasms.
B. This agent does not inhibit cyclooxygenase 1 or 2 enzymes. It lacks the peripheral anti-inflammatory, antipyretic, and antiplatelet properties characteristic of drugs like ibuprofen or aspirin. It does not reduce prostaglandin synthesis at the site of tissue injury.
C. While it may cause sedation as a side effect, it is not indicated for the clinical management of generalized anxiety disorder. It does not modulate gamma-aminobutyric acid receptors in the same manner as benzodiazepines. Its use is strictly regulated.
D. Hydromorphone HCl is a potent mu-opioid receptor agonist within the central nervous system. It alters the perception of and emotional response to pain by inhibiting ascending pain pathways. This mechanism of action defines its classification as an opioid analgesic.
Correct Answer is C
Explanation
A. Flexeril is the brand name for cyclobenzaprine hydrochloride, a skeletal muscle relaxant. It acts on the locus coeruleus to reduce tonic somatic motor activity. It does not possess the antimetabolite properties characteristic of the drug methotrexate specified in the question.
B. Xalatan is the brand name for latanoprost, a prostaglandin F2-alpha analog used in ophthalmology. It increases uveoscleral outflow to reduce intraocular pressure. It is not chemically or therapeutically related to the folic acid antagonist methotrexate mentioned in the question stem.
C. Trexall is a proprietary brand name for methotrexate, an antimetabolite and antifolate agent. It competitively inhibits dihydrofolate reductase, preventing the conversion of dihydrofolate to tetrahydrofolate. This action disrupts DNA synthesis and cellular replication in neoplastic and inflammatory cells.
D. Zanaflex is the brand name for tizanidine, a central alpha-2 adrenergic agonist used for spasticity. It increases presynaptic inhibition of motor neurons to reduce muscle tone. It lacks the immunosuppressive and cytotoxic mechanisms of action that define the molecule methotrexate.
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