What stimulates the kidney to release erythropoietin EPO?
Low level of iron concentration in the blood
Low level of oxygen concentration in the blood
Low number of red blood cells in the blood
High number of red blood cells in the blood
The Correct Answer is B
a) Low level of iron concentration in the blood: Iron is necessary for hemoglobin synthesis, but it does not directly stimulate EPO production.
b) Low level of oxygen concentration in the blood: Hypoxia is the primary stimulus for EPO release, which then promotes red blood cell production to increase oxygen-carrying capacity.
c) Low number of red blood cells in the blood: While anemia can lead to hypoxia, it is the oxygen deficit (not RBC count itself) that directly stimulates EPO.
d) High number of red blood cells in the blood: This would decrease EPO production through negative feedback.
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Related Questions
Correct Answer is A,C,B,E,D
No explanation
Correct Answer is A
Explanation
a) Hormonal: This refers to the stimulation of one endocrine gland by hormones released from another gland. GnRH from the hypothalamus stimulates the anterior pituitary to release LH/FSH, which then stimulate the ovaries to secrete estrogen. Thus, this is hormonal control.
b) Neural: Neural stimulation involves direct innervation (e.g., adrenal medulla stimulated by the sympathetic nervous system), which does not apply here.
c) Negative Feedback: This refers to a regulatory mechanism, not the initial cause of estrogen secretion. Estrogen can negatively feedback on GnRH, but that’s not the mechanism being asked.
d) Humoral: Humoral stimuli refer to changes in blood levels of ions or nutrients (e.g., calcium regulating PTH), not hormones.
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