Which chronic complication of diabetes mellitus is characterized by the thickening and narrowing of small blood vessels, leading to impaired blood flow to the lower extremities?
Diabetic ketoacidosis (DKA).
Diabetic nephropathy.
Diabetic neuropathy.
Peripheral arterial disease (PAD).
The Correct Answer is D
Peripheral arterial disease (PAD) is a chronic complication of diabetes mellitus that results from the thickening and narrowing of small blood vessels, leading to reduced blood flow to the lower extremities. This can cause symptoms such as leg pain, numbness, and poor wound healing.
Incorrect choices:
a. This choice is incorrect. Diabetic ketoacidosis (DKA) is an acute complication characterized by high blood glucose levels, ketosis, and metabolic acidosis.
b. This choice is incorrect. Diabetic nephropathy is a chronic complication that affects the kidneys and can lead to impaired kidney function.
c. This choice is incorrect. Diabetic neuropathy refers to nerve damage due to diabetes and can cause symptoms such as tingling, pain, and loss of sensation in the extremities.
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Related Questions
Correct Answer is C
Explanation
Type 1 diabetes is characterized by the autoimmune destruction of pancreatic beta cells, leading to a lack of insulin production. This results in an absolute insulin deficiency and requires external insulin administration.
Incorrect choices:
a. This choice is incorrect. Insulin resistance is a characteristic of type 2 diabetes, not type 1.
b. This choice is incorrect. Type 1 diabetes is not primarily caused by lifestyle factors; it has an autoimmune etiology.
d. This choice is incorrect. Type 1 diabetes typically develops in childhood or adolescence, not adulthood, and is not associated with insulin resistance.
Correct Answer is B
Explanation
Basal-bolus insulin therapy involves administering a continuous basal insulin infusion to provide background insulin coverage and delivering bolus doses of insulin before meals to cover postprandial glucose elevations.
Incorrect choices:
a. This choice is incorrect. Oral antidiabetic medications are not used in basal-bolus insulin therapy.
c. This choice is incorrect. Sliding-scale insulin therapy involves adjusting insulin doses based on current blood glucose levels, rather than providing consistent basal and mealtime coverage.
d. This choice is incorrect. Insulin glargine therapy provides long-acting basal insulin coverage but does not involve bolus doses before meals.
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