Which effect of protein binding on drugs in the bloodstream is accurate?.
Inactivation of the drug.
Increased risk of allergic reaction.
Precipitation of an idiosyncratic reaction.
Accumulation of the drug.
The Correct Answer is D
Choice A rationale:
Protein binding does not inactivate the drug. Instead, it can affect the drug’s distribution and bioavailability.
Choice B rationale:
Protein binding does not directly increase the risk of an allergic reaction. Allergic reactions are typically immune responses to a drug, not a result of protein binding.
Choice C rationale:
An idiosyncratic reaction is an unusual or unexpected reaction to a drug, which is not related to protein binding.
Choice D rationale:
Protein binding can lead to the accumulation of the drug. Drugs often cannot cross membranes mainly due to the high molecular mass of the drug-protein complex, resulting in the accumulation of the active compounds.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
While it’s true that hydration affects skin absorption, it’s not accurate to say that water-soluble drugs are not readily absorbed because the skin is not fully hydrated.
Choice B rationale:
Inflammation can actually increase the amount of drug absorbed due to increased blood flow and permeability.
Choice C rationale:
Topical administration with percutaneous absorption can be effective in infants, but it’s not always the case.
Choice D rationale:
Infants wearing plastic-coated diapers are indeed more susceptible to skin absorption. This is because the occlusive nature of the diaper can enhance absorption by increasing the hydration of the skin.
Correct Answer is D
Explanation
Choice A rationale:
A Placebo is a substance that has no therapeutic effect and is used as a control in clinical trials. It does not cause birth defects.
Choice B rationale:
Carcinogens are substances capable of causing cancer in living tissue, not specifically birth defects.
Choice C rationale:
Steroids can have side effects and risks, but they are not specifically known to cause birth defects.
Choice D rationale:
Teratogens are substances that can cause birth defects. This includes certain medications, chemicals, infectious diseases, and physical conditions.
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