Which factor associated with aging increases the risk of gastric irritation from nonsteroidal anti-inflammatory drugs (NSAIDS) in older adults?.
Decreased splanchnic blood flow.
Prolonged secretion of gastric acid.
Delayed gastric emptying.
Loss of cells from the gastric plexus.
The Correct Answer is C
Choice A rationale:
Decreased splanchnic blood flow can affect drug absorption and metabolism, but it does not directly increase the risk of gastric irritation from NSAIDs.
Choice B rationale:
Prolonged secretion of gastric acid can contribute to conditions like gastroesophageal reflux disease (GERD), but it is not the primary factor increasing the risk of gastric irritation from NSAIDs in older adults.
Choice C rationale:
Delayed gastric emptying is the correct answer. It allows drugs to stay in contact with the stomach lining for a longer time, which can increase the risk of gastric irritation from NSAIDs.
Choice D rationale:
Loss of cells from the gastric plexus can affect gastric function, but it is not directly linked to an increased risk of gastric irritation from NSAIDs.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale:
A decrease in blood pressure is a common side effect when a medication increases urine output, as the reduction in fluid volume can lead to lower blood pressure.
Choice B rationale:
While a decrease in blood pressure might be desired in certain conditions (like hypertension), in this context it is a side effect, not the primary desired effect.
Choice C rationale:
The therapeutic effect of the medication in this case is to increase urine output, not to decrease blood pressure.
Correct Answer is D
Explanation
Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.
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