Which statement indicates a correct understanding of topical drug absorption in a pediatric patient?.
Because the skin is not fully hydrated at this age, water-soluble drugs are not readily absorbed.
Inflammation decreases the amount of drug absorbed.
Topical administration with percutaneous absorption is usually effective in infants.
Infants wearing plastic-coated diapers are more susceptible to skin absorption.
The Correct Answer is D
Choice A rationale:
While it’s true that hydration affects skin absorption, it’s not accurate to say that water-soluble drugs are not readily absorbed because the skin is not fully hydrated.
Choice B rationale:
Inflammation can actually increase the amount of drug absorbed due to increased blood flow and permeability.
Choice C rationale:
Topical administration with percutaneous absorption can be effective in infants, but it’s not always the case.
Choice D rationale:
Infants wearing plastic-coated diapers are indeed more susceptible to skin absorption. This is because the occlusive nature of the diaper can enhance absorption by increasing the hydration of the skin.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["2"]
Explanation
The correct answer is 2 tablets. Step 1 is to divide the prescribed dose by the available dose. So, 500 mg ÷ 250 mg = 2. Rationale: The nurse needs to administer the amount of medication that will equal the prescribed dose. Since each tablet contains 250 mg of amoxicillin, two tablets will provide the 500 mg dose.
So, the correct answer is 2 tablets.
Correct Answer is D
Explanation
Choice A rationale:
While distribution can affect a person’s response to medication, it is not the aspect of genetic makeup most likely to alter this response.
Choice B rationale:
Absorption can affect how a drug is taken up by the body, but it is not the aspect of genetic makeup most likely to alter a person’s response to medication.
Choice C rationale:
Excretion, or how the body eliminates a drug, can affect drug response, but it is not the aspect of genetic makeup most likely to alter this response.
Choice D rationale:
Metabolism, or how the body processes a drug, is the aspect of genetic makeup most likely to alter a person’s response to medication. Genetic differences can lead to variations in drug-metabolizing enzymes, affecting how quickly or slowly drugs are metabolized.
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