Which individual(s) would be at risk for developing a pressure ulcer/injury? Select all that apply.

Rationale:

A. Autosomal dominant disorders do not typically skip generations. If a parent carries the dominant allele, there is a 50% chance of passing it to each child, so the trait usually appears in every generation. Skipping generations is more characteristic of autosomal recessive disorders, where individuals can be carriers without showing symptoms.

B. Autosomal dominant disorders affect both males and females equally, because the gene is located on an autosome (non-sex chromosome). There is no sex-specific pattern of inheritance.

C. Autosomal dominant disorders can manifest at any age, depending on the specific condition. Some, like Huntington disease, appear in adulthood, while others, such as Marfan syndrome, may be evident at birth or in early childhood.

D. In autosomal dominant disorders, an individual with one copy of the mutated gene will express the disorder, meaning there are no asymptomatic carriers. Each affected person shows signs of the disease, even if symptoms are mild. Carriers, by definition, are asymptomatic individuals with a recessive allele, which does not apply in dominant disorders.Top of FormBottom of Form

Rationale:

A. This describes a local infection, where the pathogen affects only one specific area, such as a skin abscess or localized wound infection. Symptoms are limited to that area.

B. This describes a subclinical or latent infection, where the pathogen is present but does not produce noticeable symptoms. It is not systemic because it does not actively spread to multiple sites.

C. A systemic infection involves the spread of pathogens or their toxins through the bloodstream or lymphatic system to multiple organs and tissues. Examples include sepsis, bacteremia, or viral infections like influenza that affect multiple organ systems. Systemic infections often cause fever, malaise, hypotension, and widespread inflammation.

D. This describes a polymicrobial infection, which can be local or systemic depending on spread, but having multiple pathogens at one site does not define systemic infection.