Which of the following are ways that pathogens can evade the immune system? (Select all that apply)
viral latency
host defense failure
immunosuppression
Immunodeficiency
Correct Answer : A,B,C,D
A. Viral Latency: Some viruses, like herpesviruses, can enter a latent phase where they hide in host cells, making it challenging for the immune system to detect and target them.
B. Host Defense Failure: This term encompasses situations where the host's defense mechanisms, including physical barriers and immune responses, are not effective in preventing or controlling infection. For example, pathogens may develop mechanisms to evade detection by the immune system.
C. Immunosuppression: Pathogens can actively suppress the host's immune response. They may produce molecules or proteins that inhibit the immune system's ability to mount an effective defense.
D. Immunodeficiency: Individuals with immunodeficiency disorders have weakened immune systems, which can be congenital (genetic) or acquired. This weakness makes them more susceptible to infections.
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Related Questions
Correct Answer is C
Explanation
A. Delayed hypersensitivity reaction: This type of hypersensitivity reaction, also known as Type IV hypersensitivity, involves a delayed response by the immune system and is mediated by T cells. It does not necessarily involve a failure of self-tolerance.
B. Antibody-mediated reaction: This type of hypersensitivity reaction, also known as Type II hypersensitivity, involves antibodies targeting specific antigens on cell surfaces, leading to cell destruction. It doesn't directly indicate a failure of self-tolerance but rather an immune response against specific cells or tissues.
C. Autoimmune reaction: In autoimmune reactions, the immune system fails to recognize certain body tissues or substances as "self," leading to an immune response against the body's own cells or tissues. This results from a breakdown in self-tolerance, where the immune system mistakenly targets its own body.
D. Immediate hypersensitivity reaction: This type of hypersensitivity reaction, also known as Type I hypersensitivity, involves an immediate response by the immune system to an allergen. It includes conditions like allergies and anaphylaxis, where the immune system reacts strongly to substances that are normally harmless. This response does not necessarily indicate a failure of self-tolerance but rather an exaggerated response to specific antigens.
Correct Answer is D
Explanation
A. Reddened tongue and gums: This side effect is not typically associated with ampicillin. However, certain medications or medical conditions can cause changes in oral tissues, leading to redness in the tongue and gums.
B. Digit numbness and tingling: Ampicillin does not commonly cause numbness and tingling in the fingers and toes. These symptoms can be associated with neurological issues or circulatory problems.
C. Bruising and petechiae: These symptoms can indicate bleeding disorders or low platelet count and are not usually caused by ampicillin. It's essential to investigate further if a patient experiences unexplained bruising or petechiae.
D. Skin rash and loose stools: Skin rash is a known side effect of penicillin-type antibiotics, including ampicillin. Loose stools or diarrhea can also occur due to disruption of the gut flora caused by the antibiotic. Patients should be aware of these possibilities and report any severe or persistent symptoms to their healthcare provider.
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