Patients with aminoglycoside therapy should be monitored for:
Ototoxicity and nephrotoxicity
ototoxicity and cardiotoxicity
Hepatotoxicity and nephrotoxicity
Cardiotoxicity and hepatotoxicity
The Correct Answer is A
A. Ototoxicity and Nephrotoxicity:
Ototoxicity: Aminoglycosides can damage the inner ear structures, leading to hearing loss and balance issues.
Nephrotoxicity: These drugs can harm the kidneys, potentially causing acute kidney injury or chronic kidney disease. Monitoring kidney function is crucial to prevent renal damage.
B. Ototoxicity and Cardiotoxicity:
Ototoxicity: As mentioned above, aminoglycosides can damage the inner ear, affecting hearing and balance.
Cardiotoxicity: Aminoglycosides primarily affect the ears and kidneys; they do not directly target the heart. Cardiotoxicity is not a common side effect associated with aminoglycosides.
C. Hepatotoxicity and Nephrotoxicity:
Hepatotoxicity: This term refers to liver damage caused by drugs or toxins. Aminoglycosides are not known to cause liver problems; their primary concern is kidney damage.
Nephrotoxicity: As mentioned earlier, aminoglycosides can harm the kidneys, which is a well-known side effect.
D. Cardiotoxicity and Hepatotoxicity:
Cardiotoxicity: This term refers to the toxic effects on the heart, leading to various heart-related issues. Aminoglycosides do not primarily affect the heart; their main concerns are the ears (ototoxicity) and kidneys (nephrotoxicity).
Hepatotoxicity: Aminoglycosides are not typically associated with liver damage. They are primarily metabolized and excreted by the kidneys, which is why kidney monitoring is crucial during their use.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Neutrophils: Neutrophils are a type of white blood cell that plays a key role in the immune system's response to infections, particularly bacterial infections. They are not primarily involved in eliminating cancer cells.
B. Eosinophils: Eosinophils are another type of white blood cell. They are important in the immune response to parasites and are also involved in allergic reactions. While they have a role in the immune system, they are not the primary cells involved in eliminating cancer cells.
C. Platelets: Platelets, also known as thrombocytes, are not cells but rather small cell fragments. They are essential for blood clotting and do not directly participate in the immune response against cancer cells.
D. Macrophages: Macrophages are a type of white blood cell that are involved in the immune system's defense against cancer. They are phagocytes, which means they engulf and digest cellular debris, foreign substances, and cancer cells. Macrophages play a crucial role in the body's immune surveillance and response against cancer.
Correct Answer is B
Explanation
A. Gut-associated lymphoid tissue (GALT): GALT is a component of the mucosa-associated lymphoid tissue (MALT) and refers to the immune cells found in the gastrointestinal tract. These cells play a significant role in local immune responses in the gut.
B. Bone marrow: The bone marrow is the primary site of blood cell production in the body. It contains stem cells that can differentiate into various blood cells, including B cells. B cells mature in the bone marrow.
C. Thymus: The thymus is an organ located near the heart and is crucial for the development of T cells. T cells mature in the thymus, where they learn to recognize self from non-self antigens.
D. Lymph nodes: Lymph nodes are small, bean-shaped structures that produce and store cells that help fight infection. While they are essential parts of the immune system, B and T cells are not originally derived from lymph nodes.
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