Which of the following can be determined using culture and sensitivity tests?
Decision to administer either a bactericidal or bacteriostatic drug
Microbial susceptibility to an anti-infective
Duration of the antibacterial drug therapy
Decision to administer empiric therapy
The Correct Answer is B
A. Decision to administer either a bactericidal or bacteriostatic drug:
Culture and sensitivity tests provide information about the susceptibility of the microorganism to specific antimicrobial agents. Based on this information, healthcare providers can choose between bactericidal (agents that kill bacteria) or bacteriostatic (agents that inhibit bacterial growth) drugs. For example, if the culture indicates that the microorganism is susceptible to a bactericidal drug, such as penicillin, the healthcare provider may choose to administer that type of drug.
B. Microbial susceptibility to an anti-infective:
This option accurately describes one of the primary purposes of culture and sensitivity tests. These tests determine whether the microorganism causing the infection is susceptible or resistant to specific antimicrobial agents. This information guides the selection of the most appropriate anti-infective therapy to effectively treat the infection.
C. Duration of the antibacterial drug therapy:
While culture and sensitivity tests provide valuable information about microbial susceptibility to antimicrobial agents, they do not specifically determine the duration of antibacterial drug therapy. The duration of therapy is often determined based on factors such as the type and severity of the infection, the patient's response to treatment, and clinical guidelines, rather than solely on the results of culture and sensitivity tests.
D. Decision to administer empiric therapy:
Empiric therapy involves the initiation of antimicrobial treatment based on clinical judgment and knowledge of likely pathogens before culture and sensitivity results are available. Culture and sensitivity tests help confirm the causative microorganism and guide subsequent treatment decisions, including adjustments to therapy based on the results. Therefore, while culture and sensitivity tests inform decisions regarding antimicrobial therapy, they do not directly determine whether empiric therapy should be initiated.
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Related Questions
Correct Answer is A
Explanation
A. She only has one functioning kidney:
This choice is the most significant consideration when prescribing vancomycin to Mrs. Oza. Vancomycin is primarily eliminated from the body through the kidneys. Individuals with reduced kidney function, such as Mrs. Oza with only one functioning kidney, have a higher risk of vancomycin-associated nephrotoxicity (kidney damage). Therefore, her renal status is crucial information for determining the appropriate dosage of vancomycin and monitoring for any signs of kidney impairment during treatment.
B. She remains outdoors for long periods of time:
While spending time outdoors for long periods may have implications for Mrs. Oza's overall health, it is not directly relevant to the prescription of vancomycin. This information may be important for considering sun exposure, hydration, and other factors related to her arthritis and general well-being, but it does not specifically impact the pharmacokinetics or pharmacodynamics of vancomycin.
C. She has hypertension:
Mrs. Oza's hypertension is a relevant medical condition to consider in her overall health management. However, hypertension alone does not directly affect the prescription of vancomycin. Hypertension may influence the choice of antihypertensive medications or other aspects of her medical care, but it does not have a direct impact on the renal clearance or potential nephrotoxicity of vancomycin.
D. She enjoys an alcoholic beverage twice a week:
While alcohol consumption can interact with certain medications and impact overall health, it is not the most significant consideration when prescribing vancomycin to Mrs. Oza. Moderate alcohol consumption is unlikely to directly affect the pharmacokinetics or pharmacodynamics of vancomycin. However, excessive alcohol intake may contribute to liver dysfunction, which could indirectly influence drug metabolism. Nonetheless, in Mrs. Oza's case, her reduced renal function is a more critical factor to consider when prescribing vancomycin.
Correct Answer is A
Explanation
A. Penicillin will be effective in treating the infection:
This interpretation is correct. When the culture and sensitivity test results show that the bacteria causing the infection are sensitive to penicillin, it means that penicillin will effectively inhibit the growth of these bacteria, leading to the resolution of the infection. This sensitivity indicates that penicillin is an appropriate and effective choice for treating the infection.
B. Penicillin will not be effective in treating the infection:
This interpretation is incorrect. If the bacteria are sensitive to penicillin, it means that penicillin will be effective in treating the infection. Sensitivity to penicillin indicates that the bacteria are susceptible to the antimicrobial activity of penicillin, and therefore, penicillin is expected to be effective in eradicating the infection.
C. The test must be repeated to obtain accurate results:
This interpretation is not warranted based on the information provided. If the culture and sensitivity test results indicate that the bacteria causing the infection are sensitive to penicillin, there is no need to repeat the test for accuracy. Sensitivity testing provides valuable information about the susceptibility of bacteria to specific antibiotics, helping healthcare providers make informed decisions about appropriate treatment.
D. Ms. Robertson is allergic to penicillin:
This interpretation is unrelated to the information provided in the scenario. The culture and sensitivity test results indicate the susceptibility of bacteria to penicillin, not whether the patient has an allergy to penicillin. Allergy testing is a separate diagnostic process used to determine if a patient is allergic to penicillin or other medications. Sensitivity testing does not provide information about the patient's allergy status.
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