Which of the following correctly lists the sequence of steps that occur during hemostasis in response to a damaged blood vessel?

a) Decreased evidence of endocytosis: Endocytosis increases in hyperthyroidism as T3/T4 are actively removed from colloid.

b) Decreased evidence of lysosomal activity: Lysosomal activity increases to process thyroglobulin into active hormones.

c) A decrease in the size of the follicular cells: Follicular cells become taller (columnar) and more active, not smaller.

d) A decrease in the cross-sectional area occupied by the colloid: In hyperthyroidism (e.g., Graves' disease), the thyroid follicles are hyperactive, so colloid is used up rapidly, reducing the colloid area.

e) Decreased number of reabsorption lacunae: These increase in number as colloid is actively resorbed.

a) Hormonal: This refers to the stimulation of one endocrine gland by hormones released from another gland. GnRH from the hypothalamus stimulates the anterior pituitary to release LH/FSH, which then stimulate the ovaries to secrete estrogen. Thus, this is hormonal control.

b) Neural: Neural stimulation involves direct innervation (e.g., adrenal medulla stimulated by the sympathetic nervous system), which does not apply here.

c) Negative Feedback: This refers to a regulatory mechanism, not the initial cause of estrogen secretion. Estrogen can negatively feedback on GnRH, but that’s not the mechanism being asked.

d) Humoral: Humoral stimuli refer to changes in blood levels of ions or nutrients (e.g., calcium regulating PTH), not hormones.