Which of the following would indicate PPROM in a 32-week pregnant patient?
Vaginal fluid that makes a fern pattern on a microscope.
White vaginal discharge.
Negative fetal fibronectin test.
Vaginal fluid with a pH of 4.5.
The Correct Answer is A
Choice A rationale
A fern pattern on a microscope slide is the definitive diagnostic sign of premature rupture of membranes (PPROM). This occurs when amniotic fluid, which contains sodium chloride, dries on the slide, forming a crystalline, fern-like pattern. This positive "ferning" test confirms the presence of amniotic fluid, indicating that the membranes have ruptured.
Choice B rationale
White vaginal discharge is a common finding during pregnancy and is not indicative of PPROM. This discharge, known as leukorrhea, is a result of increased estrogen production and blood flow to the vaginal area. It is a normal physiological change and does not signify ruptured membranes.
Choice C rationale
A negative fetal fibronectin test indicates a low probability of preterm birth within the next one to two weeks. It does not diagnose PPROM. While PPROM often leads to preterm birth, the fFN test is a predictive tool for labor, whereas ferning is a direct diagnostic test for membrane rupture.
Choice D rationale
The pH of vaginal fluid is typically acidic, ranging from 3.8 to 4.5. Amniotic fluid, however, is alkaline, with a pH of 7.0 to 7.5. Therefore, a vaginal fluid pH of 4.5 would be considered normal and would not indicate the presence of alkaline amniotic fluid, which would raise the pH to above 6.5.
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Correct Answer is B
Explanation
Choice A rationale
True labor contractions are characterized by their persistence and increasing intensity, unlike Braxton Hicks or false labor contractions which often subside with ambulation or a change in activity. This is due to the sustained release of oxytocin and prostaglandins, which stimulate continuous uterine muscle activity, leading to cervical change.
Choice B rationale
A key differentiator of true labor contractions is that they do not diminish with comfort measures like relaxation or taking a shower. These contractions are caused by physiological changes at the myometrial cellular level that are not easily influenced by external stimuli, and their progressive nature is essential for cervical effacement and dilation.
Choice C rationale
True labor contractions follow a predictable pattern, becoming regular in frequency, duration, and intensity over time. This is in contrast to false labor contractions, which remain irregular. The increasing regularity is a result of the synchronized rhythmic firing of myometrial cells as the labor process advances.
Choice D rationale
True labor contractions typically originate in the back and radiate to the lower abdomen, often described as a cramping or tightening sensation that encompasses the entire uterus. Discomfort localized only to the top of the uterus is more characteristic of Braxton Hicks contractions, which do not contribute to cervical change.
Correct Answer is D
Explanation
Choice A rationale
Polyhydramnios, an excessive amount of amniotic fluid, is associated with an increased risk of premature rupture of membranes and umbilical cord prolapse. While it can cause uterine overdistention, leading to hypotonic dysfunction, it is not a primary risk factor for uterine rupture. The excess fluid does not directly weaken the uterine wall.
Choice B rationale
Gestational diabetes can lead to macrosomia, a fetus with a birth weight greater than 4.0 kg. While a large fetus can cause a difficult delivery and increase the risk for shoulder dystocia, the primary risk for uterine rupture is related to a scarred uterus from a previous cesarean section, not fetal size alone.
Choice C rationale
Hypotonic uterine dysfunction is characterized by weak, infrequent, or ineffective contractions during active labor. The uterine muscle is not contracting with sufficient force to cause cervical change. This condition primarily prolongs labor but does not increase the risk of uterine rupture, as the uterine wall is not under excessive strain.
Choice D rationale
Uterine rupture is a serious complication, and the risk is significantly elevated with oxytocin induction, especially in patients with a history of a previous cesarean section. Oxytocin stimulates powerful uterine contractions, and if the dose is not carefully titrated, it can overstimulate the uterus, potentially causing the old scar to tear under the intense pressure.
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