Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.
Metabolism of drug by the kidneys is slower, so reduced dosage is needed.
Absorption of oral medications is more predictable but more rapid than in adults.
There's an increased risk of toxicity with use of topical agents.
Protein binding of drugs is greater than in adults.
The Correct Answer is C
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
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Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Absorption is not primarily affected by the functioning of hepatic enzymes.
Choice B rationale:
Distribution is not the main concern when dealing with abnormal functioning of hepatic enzymes.
Choice C rationale:
Excretion is mainly a function of the kidneys, not the liver.
Choice D rationale:
Metabolism is the aspect of pharmacokinetics most affected by the functioning of hepatic enzymes. The liver plays a crucial role in the metabolism of drugs.
Correct Answer is D
Explanation
Choice A rationale:
While a clinical care pathway can guide the treatment plan, it is not specifically designed to develop a detailed plan for a patient in critical condition.
Choice B rationale:
A clinical care pathway is not specifically designed as a communication tool for nurses, but for all healthcare professionals involved in a patient’s care.
Choice C rationale:
A clinical care pathway does not document the plan for admission, but rather the standardized care plan for a specific condition.
Choice D rationale:
A clinical care pathway is indeed a standardized care plan derived from “best practice” patterns.
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