Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.
Metabolism of drug by the kidneys is slower, so reduced dosage is needed.
Absorption of oral medications is more predictable but more rapid than in adults.
There's an increased risk of toxicity with use of topical agents.
Protein binding of drugs is greater than in adults.
The Correct Answer is C
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
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Related Questions
Correct Answer is D
Explanation
Choice A rationale:
A Placebo is a substance that has no therapeutic effect and is used as a control in clinical trials. It does not cause birth defects.
Choice B rationale:
Carcinogens are substances capable of causing cancer in living tissue, not specifically birth defects.
Choice C rationale:
Steroids can have side effects and risks, but they are not specifically known to cause birth defects.
Choice D rationale:
Teratogens are substances that can cause birth defects. This includes certain medications, chemicals, infectious diseases, and physical conditions.
Correct Answer is C
Explanation
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
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