Which principle of pharmacokinetics must the nurse keep in mind when administering medication to an infant?.
Metabolism of drug by the kidneys is slower, so reduced dosage is needed.
Absorption of oral medications is more predictable but more rapid than in adults.
There's an increased risk of toxicity with use of topical agents.
Protein binding of drugs is greater than in adults.
The Correct Answer is C
Choice A rationale:
While it’s true that infants have slower drug metabolism, this is generally due to liver immaturity, not kidney function.
Choice B rationale:
Absorption of oral medications in infants can be unpredictable due to their immature digestive systems.
Choice C rationale:
Infants do have an increased risk of toxicity with the use of topical agents because their skin is thinner and more permeable.
Choice D rationale:
Protein binding of drugs is actually less in infants than in adults, not greater.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
An allergic reaction refers to an immune response to a foreign substance. It does not describe the interaction between an antacid and ketoconazole.
Choice B rationale:
Displacement refers to one drug replacing another at the drug-binding site on proteins, altering the distribution of the displaced drug. It does not describe the interaction between an antacid and ketoconazole.
Choice C rationale:
Accumulation refers to the buildup of a drug in the body due to inadequate metabolism or excretion. It does not describe the interaction between an antacid and ketoconazole.
Choice D rationale:
A drug interaction occurs when the effect of one drug is altered by the administration of another drug. Antacids can slow the dissolution and absorption of ketoconazole, which is a type of drug interaction.
Correct Answer is C
Explanation
Choice A rationale:
The fourth phase of the nursing process is planning.
Choice B rationale:
The third phase of the nursing process is diagnosis.
Choice C rationale:
The second phase of the nursing process is diagnosis.
Choice D rationale:
The first phase of the nursing process is assessment.
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