Which factors affect the gastrointestinal absorption of medicines? (Select all that apply.) Select 4 options.

(Select All that Apply.).

Choice A rationale:
Using a follow-up rinse with a flavored drink is a common practice when administering oral medication to a preschool child. This helps mask the taste of the medication, making it more palatable for the child.
Choice B rationale:
Placing the capsule or tablet under the tongue (sublingual administration) is not typically recommended for preschool children due to the risk of choking.
Choice C rationale:
Supporting the child’s head and holding the child in the lap can be helpful but is not a specific guideline for administering oral medication.
Choice D rationale:
Using chewable tablets can be an option if the child’s teeth are not loose. However, it’s not a general guideline as not all medications come in chewable form.

Choice A rationale:
While it’s true that hydration affects skin absorption, it’s not accurate to say that water-soluble drugs are not readily absorbed because the skin is not fully hydrated.
Choice B rationale:
Inflammation can actually increase the amount of drug absorbed due to increased blood flow and permeability.
Choice C rationale:
Topical administration with percutaneous absorption can be effective in infants, but it’s not always the case.
Choice D rationale:
Infants wearing plastic-coated diapers are indeed more susceptible to skin absorption. This is because the occlusive nature of the diaper can enhance absorption by increasing the hydration of the skin.