Which factors affect the gastrointestinal absorption of medicines? (Select all that apply.) Select 4 options.

(Select All that Apply.).

Choice A rationale:
An allergic reaction refers to an immune response to a foreign substance. It does not describe the interaction between an antacid and ketoconazole.
Choice B rationale:
Displacement refers to one drug replacing another at the drug-binding site on proteins, altering the distribution of the displaced drug. It does not describe the interaction between an antacid and ketoconazole.
Choice C rationale:
Accumulation refers to the buildup of a drug in the body due to inadequate metabolism or excretion. It does not describe the interaction between an antacid and ketoconazole.
Choice D rationale:
A drug interaction occurs when the effect of one drug is altered by the administration of another drug. Antacids can slow the dissolution and absorption of ketoconazole, which is a type of drug interaction.

Choice A rationale:
The term “Aged” is not a specific life stage and can refer to anyone who is old, without specifying an age range.
Choice B rationale:
“Elderly” is often used to refer to individuals who are in their 80s or 90s, which is older than 653.
Choice C rationale:
“Adult” typically refers to individuals in the age range of 18 to 64 years, so a 65-year-old would not fall into this category.
Choice D rationale:
“Older adult” is a term often used to refer to individuals who are 65 years and older. So, the correct answer is Choice D, Older adult.