A 22-year-old woman diagnosed with bipolar disorder missed her last two appointments with the PMHNP after she was started on lithium (Eskalith). Her mother brought her to a third appointment. The patient was excited to see the PMHNP, as evidenced by her rapid rate of speech and discussion about the book she was writing. The patient went on to say that God had spoken directly to her and given her a message that only she could give to the world. She said she hadn’t been able to sleep for at least 1 week because she had been so busy working on this book, but she felt “absolutely incredible” despite her lack of sleep. Both the patient and the mother insist she has not stopped taking her medication. The PMHNP orders laboratory studies, including a lithium level. Which level of lithium will be subtherapeutic and indicate a need for an increased dose?
5 mEq/L
0.5 mEq/L
1.2 mEq/L
15 mEq/L
The Correct Answer is B
Choice A reason: A lithium level of 5 mEq/L is critically high and would indicate severe toxicity, not subtherapeutic dosing.
Choice B reason: A lithium level of 0.5 mEq/L is at the low end or below the therapeutic range for acute mania (0.8–1.2 mEq/L), suggesting subtherapeutic dosing and a need for an increased dose.
Choice C reason: A lithium level of 1.2 mEq/L is within the therapeutic range for acute mania and would not indicate underdosing.
Choice D reason: A lithium level of 15 mEq/L is lethally toxic and requires immediate medical intervention, not dose escalation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Sam-e is primarily used for depression and joint pain. While it may have mild anticoagulant effects, it is not as significant in potentiating warfarin’s effects as omega-3 fatty acids.
Choice B reason: This choice is correct because omega-3 fatty acids have antiplatelet properties and can increase the risk of bleeding when combined with warfarin. Patients on anticoagulants are typically advised to limit or discontinue omega-3 supplementation.
Choice C reason: Melatonin is a sleep-regulating supplement and does not significantly affect coagulation or interact with warfarin to increase bleeding risk.
Choice D reason: Tryptophan is an amino acid precursor to serotonin used for sleep or mood regulation. It does not have a clinically significant interaction with warfarin.
Correct Answer is D
Explanation
Choice A reason: Decreased need for sleep can be present in both hypomania and mania; it does not differentiate the two.
Choice B reason: Irritability is also common in both hypomanic and manic episodes and is not specific for hypomania.
Choice C reason: Psychotic symptoms, such as delusions or hallucinations, are indicative of mania, not hypomania.
Choice D reason: Increased productivity, heightened energy, and elevated mood without significant functional impairment or psychotic features suggest a hypomanic episode rather than full mania.
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