A child with growth failure is receiving somatropin (rDNA origin) 1.25 mg subcutaneously (subQ) daily. The nurse reconstitutes the vial with 5 mL of bacteriostatic water for injection to yield a solution concentration of 5 mg/mL. How many mL should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest hundredth.)
The Correct Answer is ["0.25"]
Here's how to calculate the volume (mL) the nurse should administer for somatropin:
1. We know the following:
Prescribed dose: 1.25 mg somatropin (given)
Concentration after reconstitution: 5 mg/mL (given)
2. We need to find the volume (mL) to administer for the prescribed dose (1.25 mg) considering the concentration (5 mg/mL) of the reconstituted solution.
Volume to administer (mL): Dose (mg) / Concentration (mg/mL)
Volume to administer (mL): 1.25 mg / 5 mg/mL
Volume to administer (mL) = 0.25 mL (round to nearest hundredth)
Therefore, the nurse should administer 0.25 mL of the reconstituted somatropin solution subcutaneously.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["0.5"]
Explanation
Here's how to calculate the volume (mL) of filgrastim the nurse should administer:
1. Client weight conversion:
Client weight: 132 pounds
Medication dosage is based on weight per kilogram (kg).
Conversion factor: 1 kg = 2.205 lbs
Client weight (kg): 132 pounds / 2.205 lbs/kg = 60 kg (round to nearest whole number)
2. Filgrastim dosage:
Prescribed dose: 5 mcg/kg/day (given)
3. Daily filgrastim amount:
Daily dose (mcg) = Dose (mcg/kg/day) x Client weight (kg)
Daily dose (mcg) = 5 mcg/kg/day * 60 kg
Daily dose (mcg) = 300 mcg (round to nearest whole number)
4. Filgrastim vial concentration:
The medication is available in 480 mcg/0.8 mL. This indicates the concentration of filgrastim in the vial is 480 mcg per 0.8 mL.
5. We need to find the volume (mL) to administer that provides the daily dose (300 mcg) based on the medication concentration (480 mcg/0.8 mL).
Volume to administer (mL) = Daily dose (mcg) / Concentration (mcg/mL)
Volume to administer (mL) = 300 mcg / (480 mcg/0.8 mL)
To perform the division accurately, we need the concentration in the same units (mcg/mL) for both the numerator and denominator.
We can achieve this by multiplying the vial concentration (480 mcg/0.8 mL) by a factor that converts the denominator (0.8 mL) to 1 mL.
Factor = 1 mL / 0.8 mL = 1.25 (since 1.25 x 0.8 mL = 1 mL)
Apply the factor to adjust the concentration in the denominator:
Adjusted concentration = 480 mcg/0.8 mL * 1.25 = 600 mcg/mL
Now, calculate the volume to administer:
Volume to administer (mL) = 300 mcg / (600 mcg/mL)
Volume to administer (mL) = 0.5 mL (round to nearest tenth as requested)
Therefore, the nurse should administer approximately 0.5 mL of filgrastim subcutaneously.
Correct Answer is ["4.8"]
Explanation
The vial is labeled as “100 mg per 4 mL.”
This means that each mL contains 25 mg of the medication (100 mg / 4 mL = 25 mg/mL).
The nurse needs to administer 120 mg of the medication.
To find out how many mL this is, we divide the dose by the concentration:
VolumeinmL = 120mg / 25mg/mL = 4.8mL
If rounding is required to the nearest tenth, the nurse should administer 4.8 mL of the medication.
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