A client asks why she needs to take a medication on an empty stomach. The nurse explains that food generally has which effect on drug dissolution and absorption?

Does not have an effect

Increases

Decreases

Enhances

Answer and Explanation

The Correct Answer is C

A) Does not have an effect: Food can significantly affect drug dissolution and absorption, so it is not accurate to say it has no effect. The presence of food in the gastrointestinal tract can alter how drugs are absorbed.

B) Increases: While food can sometimes increase the absorption of certain medications by stimulating digestive processes, it generally does not increase drug absorption for all medications. In many cases, food can delay or decrease the rate of drug absorption.

C) Decreases: Food commonly decreases the rate and extent of drug absorption. This can occur because food may bind to the drug, alter the pH of the stomach, or affect gastric emptying, leading to reduced drug dissolution and absorption.

D) Enhances: Food generally does not enhance drug dissolution and absorption for most medications. While some medications are better absorbed with food, in many cases, food can reduce the rate at which a drug is absorbed, leading to decreased efficacy.

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Free Nursing Study Resources

Correct Answer is ["13.3"]

Explanation

Let's calculate the dosage step-by-step:

1. Determine the total daily dosage:
20 mg/dose x 4 doses/day = 80 mg/day

2. Calculate the volume needed for one dose:
20 mg / 1.5 mg/mL = 13.33 mL

3. Round to the nearest tenth:
13.33 L ≈ 13.3 mL

A. Increase the duration of action of the medication B. Decrease the frequency of subsequent doses. C. Achieve therapeutic drug levels more rapidly D. Minimize the risk of adverse effects

Correct Answer is C

Explanation

A. Increase the duration of action of the medication:
A loading dose is not intended to increase the duration of action of a medication. Instead, it aims to rapidly achieve therapeutic levels in the bloodstream. The duration of action is primarily influenced by the drug's half-life and how it's metabolized and excreted, rather than the initial dose.

B. Decrease the frequency of subsequent doses:
The primary goal of a loading dose is to reach therapeutic levels quickly, not necessarily to alter the frequency of future doses. While a loading dose can help achieve therapeutic levels faster, the dosing schedule is determined by the drug's pharmacokinetics and the condition being treated.

C. Achieve therapeutic drug levels more rapidly:
The main purpose of a loading dose is to quickly achieve a concentration of the medication in the blood that is sufficient to be therapeutic. By giving a larger initial dose, the medication reaches effective levels faster compared to gradually reaching those levels with smaller, incremental doses.

D. Minimize the risk of adverse effects:
Minimizing adverse effects is not the primary aim of a loading dose. While achieving therapeutic levels quickly may indirectly help in reducing symptoms and improving outcomes, the main purpose of a loading dose is to reach effective drug levels promptly, not specifically to reduce adverse effects.

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A client asks why she needs to take a medication on an empty stomach. The nurse explains that food generally has which effect on drug dissolution and absorption?

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Naxlex Comprehensive Predictor Exams

The healthcare provider orders Ceftriaxone 20 mg IV every 6 hours. The instructions say to reconstitute 10 mg of Ceftriaxone with 6.5 ml of normal saline for a final concentration of 5 mg/ml. How many mL would the nurse administer? (Round to the nearest tenth)

Correct Answer is ["13.3"]

Explanation

The healthcare provider orders azithromycin (Zithromax) 1000mg to be given as a loading dose. The nurse understands that the purpose of this loading dose is to:

Correct Answer is C

Explanation

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