Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.
Distribution, Excretion, Absorption Metabolism
Absorption, Excretion, Metabolism, Distribution
Absorption, Distribution, Metabolism. Excretion
Absorption, Metabolism, Distribution, Excretion
The Correct Answer is C
A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.
B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.
C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys
D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) The nurse reports the error to the physician and the charge nurse but does not document the error due to possible legal action: Ethical reporting includes thorough documentation of the error, regardless of potential legal implications. Failing to document the error could compromise patient safety and the quality of care, and it does not fulfill the requirement for transparent and comprehensive reporting.
B) The nurse does not report or document the error, since the error did not result in any harm to the patient: Ethical reporting of medication errors involves documenting and reporting all errors, regardless of whether harm occurred. This helps in preventing future errors and maintaining a culture of safety and accountability.
C) The nurse does not report the error, because the error was caught and corrected prior to drug administration: Even if the error was corrected before administration, it is crucial to report and document the incident. This practice helps identify potential systemic issues and improve safety protocols.
D) The nurse informs the patient, documents the error as per hospital policy, and notifies the physician: This action demonstrates ethical reporting as it includes informing the patient about the error, thoroughly documenting it according to hospital policy, and notifying the physician. This comprehensive approach ensures transparency, patient safety, and adherence to institutional guidelines.
Correct Answer is C
Explanation
A. Increase the duration of action of the medication:
A loading dose is not intended to increase the duration of action of a medication. Instead, it aims to rapidly achieve therapeutic levels in the bloodstream. The duration of action is primarily influenced by the drug's half-life and how it's metabolized and excreted, rather than the initial dose.
B. Decrease the frequency of subsequent doses:
The primary goal of a loading dose is to reach therapeutic levels quickly, not necessarily to alter the frequency of future doses. While a loading dose can help achieve therapeutic levels faster, the dosing schedule is determined by the drug's pharmacokinetics and the condition being treated.
C. Achieve therapeutic drug levels more rapidly:
The main purpose of a loading dose is to quickly achieve a concentration of the medication in the blood that is sufficient to be therapeutic. By giving a larger initial dose, the medication reaches effective levels faster compared to gradually reaching those levels with smaller, incremental doses.
D. Minimize the risk of adverse effects:
Minimizing adverse effects is not the primary aim of a loading dose. While achieving therapeutic levels quickly may indirectly help in reducing symptoms and improving outcomes, the main purpose of a loading dose is to reach effective drug levels promptly, not specifically to reduce adverse effects.
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