Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.

Distribution, Excretion, Absorption Metabolism

Absorption, Excretion, Metabolism, Distribution

Absorption, Distribution, Metabolism. Excretion

Absorption, Metabolism, Distribution, Excretion

Answer and Explanation

The Correct Answer is C

A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.

B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.

C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys

D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.

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Correct Answer is ["B","C","E"]

Explanation

A) Parenteral medications are avoided due to fragility of veins: While it is true that older adults may have fragile veins, this does not mean that parenteral medications are universally avoided. Parenteral medications are still used based on clinical needs, though careful consideration is given to the condition of the veins.

B) Older adults are at risk for drug toxicity due to accumulation in the body: This is correct. As people age, their liver and kidney functions often decline, leading to decreased metabolism and excretion of drugs. This can result in drug accumulation and an increased risk of toxicity.

C) The elderly population is susceptible to polypharmacy: This is correct. Older adults often take multiple medications for various chronic conditions, increasing the risk of drug interactions, side effects, and complications. Polypharmacy is a common issue in this population.

D) Medication metabolism tends to be faster in older adults: This is incorrect. Medication metabolism generally slows down in older adults due to decreased liver function. Slower metabolism can lead to drug accumulation and increased risk of adverse effects.

E) Older adults have delayed absorption: This is correct. Although the rate of absorption may not be significantly affected, the overall absorption can be altered due to changes in gastrointestinal function and blood flow in older adults.

A. Opioids B. Benzodiazepines C. Betablockers D. Acetaminophen

Correct Answer is {"A":{"answers":"C"},"B":{"answers":"D"},"C":{"answers":"A"},"D":{"answers":"B"}}

Explanation

Naloxone is an opioid antagonist and is used to reverse opioid overdoses.

Flumazenil is a benzodiazepine antagonist and can reverse the effects of benzodiazepines.

Glucagon can be used to treat beta-blocker overdose by increasing heart rate and blood pressure.

Acetylcysteine acts as an antidote for acetaminophen toxicity by replenishing glutathione levels to enhance non-toxic metabolism of acetaminophen.

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Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is caring for an older adult client. The nurse should recognize that which of the following considerations apply to older adults and pharmacology? (Select all that apply).

Correct Answer is ["B","C","E"]

Explanation

A charge nurse is teaching a group of nurses about the antagonist action of reversal medications. For each medication listed below, click to specify the expected reversal agent

Correct Answer is {"A":{"answers":"C"},"B":{"answers":"D"},"C":{"answers":"A"},"D":{"answers":"B"}}

Explanation

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