Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.
Distribution, Excretion, Absorption Metabolism
Absorption, Excretion, Metabolism, Distribution
Absorption, Distribution, Metabolism. Excretion
Absorption, Metabolism, Distribution, Excretion
The Correct Answer is C
A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.
B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.
C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys
D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A) Naloxone: Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression. Given that the client has overdosed on morphine and is exhibiting a critically low respiratory rate of 6/min, naloxone is the appropriate medication to administer to reverse the effects of morphine and restore normal breathing.
B) Flumazenil: Flumazenil is a benzodiazepine antagonist used to reverse the effects of benzodiazepine overdose. It is not effective for opioid overdoses, such as those caused by morphine.
C) Protamine: Protamine is used to reverse the effects of heparin, an anticoagulant, and is not relevant in the context of opioid overdose. It does not address the respiratory depression caused by morphine.
D) Epinephrine: Epinephrine is used in cases of anaphylaxis or severe allergic reactions and is not appropriate for reversing opioid overdose. It would not address the respiratory depression caused by morphine overdose.
Correct Answer is ["13.3"]
Explanation
Let's calculate the dosage step-by-step:
1. Determine the total daily dosage:
20 mg/dose x 4 doses/day = 80 mg/day
2. Calculate the volume needed for one dose:
20 mg / 1.5 mg/mL = 13.33 mL
3. Round to the nearest tenth:
13.33 L ≈ 13.3 mL
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