The nurse is caring for a client who needs to have a peak drug level drawn. The client was given an oral medication 30 minutes ago. What is the best action by the nurse?

Wait for at least another 30 minutes before calling to have the level drawn.

Schedule the level to be drawn in 8 hours

Call the lab to have the medication level drawn immediately

Arrange for the level to be drawn tomorrow since the peak time has passed.

Answer and Explanation

The Correct Answer is A

A. Wait for at least another 30 minutes before calling to have the level drawn:
For oral medications, peak drug levels are typically drawn 1 to 2 hours after administration, depending on the medication's pharmacokinetics. Since the client took the medication only 30 minutes ago, it is premature to draw the level now. Waiting an additional 30 minutes would align with the typical peak times for oral medications, ensuring that the drug level reflects its peak concentration.

B. Schedule the level to be drawn in 8 hours:
Drawing the peak level 8 hours after administration would likely be too late, as most oral medications reach their peak concentration within 1 to 2 hours. Scheduling the level for 8 hours later may result in an inaccurate measurement of the peak drug level, leading to potentially misleading clinical information.

C. Call the lab to have the medication level drawn immediately:
Drawing the level immediately after 30 minutes may not provide an accurate representation of the peak drug level. Oral medications generally reach peak levels later, and an early draw could result in a falsely low measurement that does not reflect the drug's maximum concentration.

D. Arrange for the level to be drawn tomorrow since the peak time has passed:
The peak time has not passed, as the medication was only administered 30 minutes ago. Drawing the level tomorrow would be far too late to assess the peak concentration accurately, which is essential for evaluating the effectiveness and safety of the medication.

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Correct Answer is ["C","E","F"]

Explanation

A. Nitroglycerin 10mg Sublingual Tablet:
Nitroglycerin taken sublingually (under the tongue) bypasses the gastrointestinal tract and the liver’s first-pass metabolism. It is designed to act quickly and directly enter the bloodstream through the mucous membranes, avoiding significant first-pass effect.

B. Morphine 2mg IV (Intravenously):
Morphine administered intravenously bypasses the gastrointestinal tract and liver, thus avoiding the first-pass effect entirely. The drug directly enters systemic circulation, providing immediate effect.

C. Famotidine 10mg Tablet:
Famotidine, when taken orally, undergoes significant first-pass metabolism. This means that a portion of the drug is metabolized by the liver before it reaches systemic circulation, affecting its bioavailability.

D. Nitroglycerin 4mg Sublingual Tablet:
Similar to the 10mg sublingual tablet, nitroglycerin administered sublingually bypasses the first-pass effect. The medication enters the bloodstream directly through the mucous membranes in the mouth.

E. Acetaminophen 325mg Capsule:
Acetaminophen, when taken orally, undergoes first-pass metabolism. A significant portion of the drug is metabolized in the liver before reaching systemic circulation, which can impact its overall effectiveness.

F. Diphenhydramine (Benadryl) 25mg Tablet:
Diphenhydramine, taken orally, is also affected by the first-pass effect. As with other oral medications, a part of the drug is metabolized by the liver before reaching systemic circulation, which can affect its efficacy and bioavailability.

A. Distribution, Excretion, Absorption Metabolism B. Absorption, Excretion, Metabolism, Distribution C. Absorption, Distribution, Metabolism. Excretion D. Absorption, Metabolism, Distribution, Excretion

Correct Answer is C

Explanation

A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.

B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.

C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys

D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.

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The nurse is caring for a client who needs to have a peak drug level drawn. The client was given an oral medication 30 minutes ago. What is the best action by the nurse?

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Naxlex Comprehensive Predictor Exams

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Correct Answer is ["C","E","F"]

Explanation

Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.

Correct Answer is C

Explanation

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