A client has been placed on corticosteroid therapy for Addison's disease. The nurse should be aware of which of the following side effects associated with this type of therapy? (Select all that apply)

Weight loss

Poor wound healing

Hypertension

Hypotension

Alterations in glucose metabolism

Answer and Explanation

Correct Answer : B,C,E

Reasoning:

Choice A reason: Weight loss is not a typical side effect of corticosteroid therapy for Addison’s disease. Corticosteroids mimic cortisol, promoting weight gain through increased appetite and fat redistribution. Weight loss is more common in untreated Addison’s disease due to cortisol deficiency and reduced appetite.

Choice B reason: Poor wound healing is a side effect of corticosteroids, as they suppress immune responses and inhibit collagen synthesis. This impairs fibroblast activity and tissue repair, increasing infection risk and delaying wound closure, a significant concern for patients on long-term therapy for Addison’s disease.

Choice C reason: Hypertension is a common side effect of corticosteroids due to their mineralocorticoid effects, which increase sodium and water retention, elevating blood volume and pressure. This is particularly relevant in Addison’s disease treatment, where corticosteroids restore deficient aldosterone and cortisol, potentially causing fluid overload.

Choice D reason: Hypotension is not a side effect of corticosteroid therapy but a symptom of untreated Addison’s disease due to aldosterone deficiency, causing sodium loss and hypovolemia. Corticosteroid therapy corrects this, so hypotension is unlikely unless under-dosed or during acute crisis.

Choice E reason: Alterations in glucose metabolism are a side effect of corticosteroids, which induce insulin resistance and increase gluconeogenesis, leading to hyperglycemia. In Addison’s disease, corticosteroids replace deficient cortisol, but excess dosing can mimic Cushing’s syndrome, causing elevated blood glucose and requiring careful monitoring.

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Correct Answer is C

Explanation

Reasoning:

Choice A reason: Elimination of iron by the body is not a typical cause of anemia in older adults. Iron is tightly regulated, and excessive loss occurs through bleeding, not spontaneous elimination. Anemia in the elderly is more commonly due to chronic blood loss or impaired absorption, not iron excretion.

Choice B reason: Excessive coffee or tea consumption can inhibit iron absorption due to tannins binding dietary iron, but it is not a primary cause of anemia in older adults. Blood loss or chronic disease are more common culprits, making dietary inhibition a less likely contributor in this population.

Choice C reason: Blood loss from the gastrointestinal or genitourinary tract is a common cause of anemia in older adults. Chronic bleeding from ulcers, colon cancer, or urinary tract issues depletes iron stores, leading to iron deficiency anemia, a frequent finding in the elderly due to higher prevalence of these conditions.

Choice D reason: A decrease in total body iron stores with age is not a primary cause of anemia. While absorption may decline slightly, blood loss from gastrointestinal or genitourinary sources is a more significant contributor in older adults, as it directly reduces iron available for hemoglobin synthesis.

A. Normal hematocrit B. Low hematocrit C. High hematocrit D. Normal blood smear

Correct Answer is B

Explanation

Reasoning:

Choice A reason: Normal hematocrit is not typical in sickle cell anemia, a hemolytic disorder where red blood cells are destroyed prematurely due to abnormal hemoglobin (HbS). Chronic hemolysis reduces red blood cell mass, lowering hematocrit, making a normal value inconsistent with the disease’s pathophysiology.

Choice B reason: Low hematocrit is characteristic of sickle cell anemia due to chronic hemolysis. Sickled red blood cells have a shorter lifespan, reducing circulating red blood cells and hemoglobin, resulting in a decreased hematocrit. This reflects the anemia’s impact on oxygen-carrying capacity, a hallmark of the condition.

Choice C reason: High hematocrit is not associated with sickle cell anemia. Elevated hematocrit occurs in conditions like polycythemia, where red blood cell mass increases. Sickle cell anemia causes hemolysis, reducing red blood cells and hematocrit, making a high value inconsistent with the disease.

Choice D reason: A normal blood smear is not expected in sickle cell anemia. Blood smears show sickled red blood cells, anisocytosis, and poikilocytosis due to hemoglobin S polymerization. These abnormal findings contrast with a normal smear, which would not reflect the hemolytic and morphological changes of the disease.

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A client has been placed on corticosteroid therapy for Addison's disease. The nurse should be aware of which of the following side effects associated with this type of therapy? (Select all that apply)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse is caring for an older adult client who has been admitted to the unit with anemia. What would the nurse expect the client to possibly exhibit?

Correct Answer is C

Explanation

A client with sickle cell anemia has a:

Correct Answer is B

Explanation

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