A client who is receiving intravenous amphotericin B for a fungal infection reports feeling dizzy and having chills and fever. The nurse should recognize that these manifestations indicate which of the following adverse reactions?
a) Anaphylaxis
b) Infusion reaction
c) Nephrotoxicity
d) Ototoxicity
The Correct Answer is B
Infusion reaction is a common adverse effect of amphotericin B that occurs within 1 to 3 hours of starting the infusion and causes symptoms such as fever, chills, headache, nausea, vomiting, and hypotension.
A is incorrect because anaphylaxis is a severe allergic reaction that causes symptoms such as urticaria, angioedema, bronchospasm, and shock.
C is incorrect because nephrotoxicity is another adverse effect of amphotericin B that causes renal impairment and electrolyte imbalances.
D is incorrect because ototoxicity is an adverse effect of some antibiotics such as gentamicin and vancomycin that causes hearing loss and tinnitus.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Answer: C. Intravenous injection is the fastest route for administering diphenhydramine in a severe allergic reaction because it provides immediate onset of action and avoids the first-pass metabolism in the liver.
A and B are incorrect because intramuscular and subcutaneous injections have slower absorption rates than intravenous injection and may not provide adequate relief in an emergency situation.
D is incorrect because oral administration of diphenhydramine has the slowest absorption rate and onset of action and is subject to first-pass metabolism in the liver.
Correct Answer is A
Explanation
Answer: A. Cefazolin is a cephalosporin antibiotic that has a cross-sensitivity with penicillin and should be avoided by clients who are allergic to penicillin.
B is incorrect because ciprofloxacin does not have cross-sensitivity with penicillin or sulfa drugs and can be safely administered to this client.
C is incorrect because vancomycin does not have cross-sensitivity with penicillin or sulfa drugs and can be safely administered to this client.
D is incorrect because Azithromycin does not have cross-sensitivity with penicillin or sulfa drugs and can be safely administered to this client.
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